2. Academic Validation
  3. A new phenyldilactone from Lespedeza cuneata

A new phenyldilactone from Lespedeza cuneata

  • J Asian Nat Prod Res. 2016;18(2):200-5. doi: 10.1080/10286020.2015.1061510.
Wei Jiang 1,  Ji Ye 2,  Yang-Guo Xie 1,  Ya-Ping Pan 1,  Yue Zheng 1,  Xiu-Ping Qian 1,  Hui-Zi Jin 1
Affiliations

Affiliations

  • 1 a School of Pharmacy, Shanghai Jiao Tong University , Shanghai 200240 , China.
  • 2 b School of Pharmacy, Second Military Medical University , Shanghai 20033 , China.
PMID: 26243444 DOI: 10.1080/10286020.2015.1061510
Abstract

A new phenyldilactone, maysedilactone B (1), together with twenty known compounds, were isolated from the aerial parts of Lespedeza cuneata. The structural elucidation of the isolated compounds was primarily based on HR-ESI-MS, IR and 1D and 2D NMR analyses. Compounds 1-8 and 15-21 were tested for cytotoxicity against four human tumor cell lines (A549, HCT116, SKOV3, and HepG2) using MTT method in vitro, while no significant activities were observed for the evaluated compounds.

Keywords

Leguminosae; Lespedeza cuneata; chemical constituents; cytotoxicity; phenyldilactone.

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