2. Academic Validation
  3. In vitro activity of cefteram against predominantly enteropathogenic and glucose nonfermentative gram-negatives

In vitro activity of cefteram against predominantly enteropathogenic and glucose nonfermentative gram-negatives

  • Chemotherapy. 1989;35(4):242-5. doi: 10.1159/000238677.
P Hohl 1,  A von Graevenitz,  J Zollinger-Iten
Affiliations

Affiliation

  • 1 Pharmaceutical Research Department, F. Hoffmann-La Roche, Basel, Switzerland.
PMID: 2766865 DOI: 10.1159/000238677
Abstract

Cefteram (T-2525), the free acid of the orally active cephalosporin ester cefteram pivoxil, was tested in vitro against 355 gram-negative clinical isolates of enteropathogenic and nonfermentative species. The compound was several times more active (w/w) against isolates belonging to the enteropathogenic Enterobacteriaceae and Vibrionaceae than against those belonging to the nonfermentative rods (excluding Pseudomonas aeruginosa).

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