2. Academic Validation
  3. Bromine isotope effects: Predictions and measurements

Bromine isotope effects: Predictions and measurements

  • Chemosphere. 2020 May;246:125746. doi: 10.1016/j.chemosphere.2019.125746.
Faina Gelman 1,  Agnieszka Dybala-Defratyka 2
Affiliations

Affiliations

  • 1 Geological Survey of Israel, Jerusalem, Israel. Electronic address: faina@gsi.gov.il.
  • 2 Institute of Applied Radiation Chemistry, Faculty of Chemistry, Lodz University of Technology, Lodz, Poland. Electronic address: agnieszka.dybala-defratyka@p.lodz.pl.
PMID: 31918087 DOI: 10.1016/j.chemosphere.2019.125746
Abstract

Brominated organic compounds (BOCs), abundant in Nature, originate from its own sources or anthropogenic activity. Many of these compounds are harmful and constitute a serious threat, therefore it is important to study and understand their behavior and fate. In situ, BOCs undergo various chemical and biochemical reactions through distinctive mechanistic pathways. However, breaking C-Br specific bond is a crucial step in the transformation of brominated organic compounds. Understanding the mechanisms of debromination can be substantially enhanced by studying Br isotope effects. In this Mini-review we provide overlook of existing experimental techniques for Br isotope analysis, discuss Br kinetic isotope effects measured for selected chemical and biochemical reactions in the LIGHT of underlying reaction mechanisms, and review the outcome from computational study of performed to provide more insightful interpretation of observed findings.

Keywords

Bromine isotopes; Bromine isotopic ratio measurements; Isotope effect; Reaction mechanism.

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