2. Academic Validation
  3. E17241 as a Novel ABCA1 (ATP-Binding Cassette Transporter A1) Upregulator Ameliorates Atherosclerosis in Mice

E17241 as a Novel ABCA1 (ATP-Binding Cassette Transporter A1) Upregulator Ameliorates Atherosclerosis in Mice

  • Arterioscler Thromb Vasc Biol. 2021 Jun;41(6):e284-e298. doi: 10.1161/ATVBAHA.120.314156.
Yanni Xu (许艳妮) # 1,  Chang Liu (刘畅) # 1,  Xiaowan Han (韩小婉) # 1 2,  Xiaojian Jia (贾晓健) 1,  Yongzhen Li (李永臻) 1,  Chao Liu (刘超) 1,  Ni Li (李霓) 1 2,  Lunming Liu (刘伦铭) 1,  Peng Liu (刘鹏) 1,  Xinhai Jiang (姜新海) 1,  Weizhi Wang (王伟志) 1,  Xiao Wang (王潇) 1,  Yining Li (李依宁) 1,  Mingzhu Chen (陈明珠) 1,  Jinque Luo (罗金雀) 1,  Xuan Zuo (左璇) 1,  Jiangxue Han (韩江雪) 1,  Li Wang (王丽) 1,  Yu Du (杜郁) 1,  Yang Xu (徐扬) 1,  Jian-Dong Jiang (蒋建东) 1 2,  Bin Hong (洪斌) 1,  Shuyi Si (司书毅) 1
Affiliations

Affiliations

  • 1 NHC Key Laboratory of Biotechnology of Antibiotics, National Center for New Microbial Drug Screening, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS&PUMC), Beijing, China (Y.X., C.L., X.H., X. Jia, Y.L., C.L., N.L., L.L., P.L., X. Jiang, W.W., X.W., Y.L., M.C., J.L., X.Z., J.H., L.W., Y.D., Y.X., J.-D.J., B.H., S.S.).
  • 2 State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, CAMS&PUMC, Beijing, China (X.H., N.L., J.-D.J.).
  • # Contributed equally.
PMID: 33441025 DOI: 10.1161/ATVBAHA.120.314156
Abstract

[Figure: see text].

Keywords

atherosclerosis; cardiovascular disease; cholesterol; drug discovery; macrophages.

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