2. Academic Validation
  3. Research status of Bacillus phytase

Research status of Bacillus phytase

  • 3 Biotech. 2021 Sep;11(9):415. doi: 10.1007/s13205-021-02964-9.
Ting Zhao # 1 2,  Xihao Yong # 1 3,  Ziming Zhao 3,  Vincenza Dolce 4,  Yuan Li 1 5,  Rosita Curcio 4
Affiliations

Affiliations

  • 1 College of Life Science and Technology, Xinjiang University, Urumqi, China.
  • 2 National Facility for Protein Science in Shanghai, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Science, Shanghai, China.
  • 3 Faculty of Bioengineering, Sichuan University of Science and Engineering, Zigong, People's Republic of China.
  • 4 Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
  • 5 Department of Bioscience, Biotechnology and Biopharmaceutics, University of Bari, Bari, Italy.
  • # Contributed equally.
PMID: 34485008 DOI: 10.1007/s13205-021-02964-9
Abstract

Phytic acid is abundant in seeds, roots and stems of Plants, it acts as an anti-nutrient in food and feed industry, since it affects the absorption of nutrients by humans and monogastric Animals. Furthermore, phosphorus produced through its decomposition by Microorganisms can cause environmental pollution. Phytase degrades phytic acid generating precursors of inositol that can be used in clinical practice; in addition, phytase treatment can minimize the anti-nutritional effect of phytic acid. The use of phytase synthesized from Bacillus is more advantageous due to its high activity. Additionally, its good heat resistance under neutral conditions greatly fills the gap of commercial utilization of acid phytase. In this review, we summarize the latest research results on Bacillus phytase, including its physiological and biochemical characteristics, molecular structure information, calcium effects on its catalytic activity and stability, its catalytic mechanism and molecular modification.

Keywords

BPPhy; Bacillus phytase; Catalytic mechanism; Molecular modification; Molecular structure information; Physiological and biochemical characteristics.

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