2. Academic Validation
  3. Bioconversion of arteannuin B to artemisinin

Bioconversion of arteannuin B to artemisinin

  • J Nat Prod. 1993 Sep;56(9):1559-66. doi: 10.1021/np50099a015.
M S Nair 1,  D V Basile
Affiliations

Affiliation

  • 1 Department of Biological Sciences, H.H. Lehman College of CUNY, The Bronx, New York 10468.
PMID: 8254350 DOI: 10.1021/np50099a015
Abstract

Arteannuin B, which co-occurs with artemisinin, the potent antimalarial principle of the Chinese medicinal herb Artemisia annua (Asteraceae), has been converted to the latter using crude and semi-purified cell-free extracts of the leaf homogenates of the plant. Detection procedures to quantitate this bioconversion, including one that is novel which uses gcms, are detailed.

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