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  5. Melan-A/MART-1 analog

Melan-A/MART-1 analog  (Synonyms: [Leu27]-Melan-A, MART-1 (26-35))

Cat. No.: HY-P5471
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Melan-A/MART-1 analog ([Leu27]-Melan-A, MART-1 (26-35)) is a biological active peptide. (This Melan-A (26-35) analog, Leu substituted for Ala at position 27, shows better HLA-A*0201 binding properties as well as better immunogenicity and antigenicity than the natural Melan-A (26-35).Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)

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Melan-A/MART-1 analog Chemical Structure

Melan-A/MART-1 analog Chemical Structure

CAS No. : 204060-45-7

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Melan-A/MART-1 analog Related Antibodies

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Description

Melan-A/MART-1 analog ([Leu27]-Melan-A, MART-1 (26-35)) is a biological active peptide. (This Melan-A (26-35) analog, Leu substituted for Ala at position 27, shows better HLA-A*0201 binding properties as well as better immunogenicity and antigenicity than the natural Melan-A (26-35).Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)

Molecular Weight

985.18

Formula

C45H80N10O14
CAS No.
Sequence

Glu-Leu-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val
Sequence Shortening

ELAGIGILTV
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Melan-A/MART-1 analog Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Melan-A/MART-1204060-45-7[Leu27]-Melan-A, MART-1 (26-35)OthersInhibitorinhibitorinhibit

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