2. Anti-infection
  3. Beta-lactamase
  4. Metallo-β-lactamase-IN-15

Metallo-β-lactamase-IN-15 (Compound ±13) is a potent MBL inhibitor, the IC50 values for NDM-1、IMP-1 and VIM-2 were 0.29 μM, 0.088 μM and 0.063 μM, respectively.

For research use only. We do not sell to patients.

Metallo-β-lactamase-IN-15 Chemical Structure

Metallo-β-lactamase-IN-15 Chemical Structure

CAS No. : 1804934-57-3

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Metallo-β-lactamase-IN-15 Related Antibodies

Top Publications Citing Use of Products

View All Beta-lactamase Isoform Specific Products:

View All Isoforms
Metallo-β-lactamase

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Metallo-β-lactamase-IN-15 (Compound ±13) is a potent MBL inhibitor, the IC50 values for NDM-1、IMP-1 and VIM-2 were 0.29 μM, 0.088 μM and 0.063 μM, respectively[1].

IC50 & Target

NDM-1

0.29 μM (IC50)

VIM-2

0.063 μM (IC50)

IMP-1

0.088 μM (IC50)

In Vitro

Metallo-β-lactamase-IN-15 (Compound ±13) (50 ug/mL; 100 ug/mL) was not toxic to L929 cells[1].
Metallo-β-lactamase-IN-15 has good bioavailability and plasma stability[1].
Metallo-β-lactamase-IN-15 (100 μg/mL;1h, 3h, 5h) growth activity of NDM-1-expressing E.coli DH5α strain, Metallo-β-lactamase-IN-15 restored imipenem activity in vitro[1].
Metallo-β-lactamase-IN-15 (100 μg/mL) decreased the minimum inhibitory concentration of meropenem in clinical E.coli DH5α strain[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Metallo-β-lactamase-IN-15 Related Antibodies

Cell Line:
Concentration:
Incubation Time:
Result:

Cell Line:
Concentration:
Incubation Time:
Result:

Cell Viability Assay

Cell Line: E.coli DH5α cells
Concentration: 100 ug/mL
Incubation Time: 1h, 3h, 5h
Result: Metallo-β-lactamase-IN-15 restored imipenem activity[1].

Cell Line:
Concentration:
Incubation Time:
Result:

Cell Line:
Concentration:
Incubation Time:
Result:
Molecular Weight

241.40

Formula

C10H11NS3
CAS No.
SMILES

SC[C@H]1SC[C@]2([H])SC3=CC=CC=C3N21
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Metallo-β-lactamase-IN-15 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Metallo-β-lactamase-IN-151804934-57-3Beta-lactamaseβ-lactamaseAntimicrobial resistanceMBL inhibitorsBBH inhibitors.Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Metallo-β-lactamase-IN-15
Cat. No.:
HY-161310
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (0 KB) Français - FR (0 KB) Deutsch - DE (0 KB) Norwegian - NO (0 KB) Español - ES (0 KB) Swedish - SV (0 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.