2. Anti-infection
  3. Beta-lactamase Bacterial
  4. Metallo-β-lactamase-IN-16

Metallo-β-lactamase-IN-16 (compound 18) is a sulfone containing metallo-β-lactamase inhibitor with an anti-bacterial activity. Metallo-β-lactamase-IN-16 inhibits NDM-1 (New Dehli metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona integron-encoded metallo-β-lactamase), and VIM-2 with IC50 values of 0.16 nM, 0.23 nM, 0.31 nM and 1.0 nM, respectively.

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Metallo-β-lactamase-IN-16 Chemical Structure

Metallo-β-lactamase-IN-16 Chemical Structure

CAS No. : 2058069-25-1

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Metallo-β-lactamase-IN-16 Related Antibodies

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Description

Metallo-β-lactamase-IN-16 (compound 18) is a sulfone containing metallo-β-lactamase inhibitor with an anti-bacterial activity. Metallo-β-lactamase-IN-16 inhibits NDM-1 (New Dehli metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona integron-encoded metallo-β-lactamase), and VIM-2 with IC50 values of 0.16 nM, 0.23 nM, 0.31 nM and 1.0 nM, respectively[1].

Molecular Weight

480.54

Formula

C16H16N8O4S3
CAS No.
SMILES

NCCS(=O)(C1=CC=C(C(C2=NNN=N2)=C1S(N)(=O)=O)C3=CC=CC4=C3N=C(S4)N)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Metallo-β-lactamase-IN-16 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Metallo-β-lactamase-IN-162058069-25-1Beta-lactamaseBacterialβ-lactamaseNDM-1IMP-1VIM-1VIM-2metallo-β-lactamase inhibitorInhibitorinhibitorinhibit

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