2. Anti-infection
  3. Beta-lactamase Bacterial
  4. Metallo-β-lactamase-IN-3

Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-3 shows high activity against VIM-1 and NDM-1, with IC50 of 0.6 and 1.0 μM, respectively. Metallo-β-lactamase-IN-3 does not show inhibition of IMP-7.

For research use only. We do not sell to patients.

Metallo-β-lactamase-IN-3 Chemical Structure

Metallo-β-lactamase-IN-3 Chemical Structure

CAS No. : 128294-71-3

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Metallo-β-lactamase-IN-3 Related Antibodies

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Description

Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-3 shows high activity against VIM-1 and NDM-1, with IC50 of 0.6 and 1.0 μM, respectively. Metallo-β-lactamase-IN-3 does not show inhibition of IMP-7[1].

IC50 & Target

IC50: 0.6 ± 0.0 μM (VIM-1), 1.0 ± 0.4 μM (NDM-1), > 10 μM (IMP-7)[1]
Molecular Weight

225.26

Formula

C10H11NO3S
CAS No.
SMILES

O=C(O)C1=CC=C(NC(CCS)=O)C=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Metallo-β-lactamase-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Metallo-β-lactamase-IN-3128294-71-3Beta-lactamaseBacterialβ-lactamaseHepG2HEK293A549low toxicityantimicrobial agentInhibitorinhibitorinhibit

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