2. Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease
  3. GABA Receptor Endogenous Metabolite
  4. Methionine-d4

Methionine-d4  (Synonyms: MRX-1024-d4; D-Methionine-d4)

Cat. No.: HY-13694S1 Purity: ≥98.0%
SDS COA Handling Instructions

Molarity Calculator

Methionine-d4 is the deuterium labeled Methionine. Methionine (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor activation.

For research use only. We do not sell to patients.

Methionine-d<sub>4</sub> Chemical Structure

Methionine-d4 Chemical Structure

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5 mg USD 190 In-stock
10 mg USD 300 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Methionine-d4:

Methionine-d4 Related Antibodies

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  • Purity & Documentation

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Description

Methionine-d4 is the deuterium labeled Methionine. Methionine (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor activation.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Methionine-d4 Related Antibodies
Molecular Weight

153.24

Formula

C5H7D4NO2S
Unlabeled CAS

348-67-4
Appearance

Solid

Color

White to off-white

SMILES

N[C@@H](C(O)=O)C([2H])([2H])C([2H])([2H])SC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 25 mg/mL (163.14 mM; Need ultrasonic)

H2O : 25 mg/mL (163.14 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.5257 mL 32.6286 mL 65.2571 mL
5 mM 1.3051 mL 6.5257 mL 13.0514 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

SDS (251 KB)

COA (250 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 6.5257 mL 32.6286 mL 65.2571 mL 163.1428 mL
5 mM 1.3051 mL 6.5257 mL 13.0514 mL 32.6286 mL
10 mM 0.6526 mL 3.2629 mL 6.5257 mL 16.3143 mL
15 mM 0.4350 mL 2.1752 mL 4.3505 mL 10.8762 mL
20 mM 0.3263 mL 1.6314 mL 3.2629 mL 8.1571 mL
25 mM 0.2610 mL 1.3051 mL 2.6103 mL 6.5257 mL
30 mM 0.2175 mL 1.0876 mL 2.1752 mL 5.4381 mL
40 mM 0.1631 mL 0.8157 mL 1.6314 mL 4.0786 mL
50 mM 0.1305 mL 0.6526 mL 1.3051 mL 3.2629 mL
60 mM 0.1088 mL 0.5438 mL 1.0876 mL 2.7190 mL
80 mM 0.0816 mL 0.4079 mL 0.8157 mL 2.0393 mL
100 mM 0.0653 mL 0.3263 mL 0.6526 mL 1.6314 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Methionine-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methionine-d4MRX-1024-d4D-Methionine-d4GABA ReceptorEndogenous MetaboliteGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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