2. Apoptosis
  3. TNF Receptor
  4. MG-C-30

MG-C-30 is an orally active agonist for CD27 with an EC50 of 0.84 μM. MG-C-30 activates NK cells and T cell co-stimulatory signals, and enhances immune response. MG-C-30 exhibits antitumor efficacy in mouse EG7-OVA model.

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MG-C-30 Chemical Structure

MG-C-30 Chemical Structure

CAS No. : 877164-43-7

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MG-C-30 Related Antibodies

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TNFRSF1A/CD120a TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF7/CD27 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

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Description

MG-C-30 is an orally active agonist for CD27 with an EC50 of 0.84 μM. MG-C-30 activates NK cells and T cell co-stimulatory signals, and enhances immune response. MG-C-30 exhibits antitumor efficacy in mouse EG7-OVA model[1].

IC50 & Target

CD27

0.84 μM (EC50)

Molecular Weight

450.55

Formula

C24H26N4O3S
CAS No.
SMILES

COC1=C(OC)C=C(C2=NC(CC(NC(C3=NC4=C(C=CC=C4)N3)C(C)C)=O)=CS2)C=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MG-C-30 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MG-C-30877164-43-7TNF ReceptorTumor Necrosis Factor ReceptorTNFRorally activeEG7-OVAC57BL/6 mouseInhibitorinhibitorinhibit

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