2. MG-V-53

MG-V-53 is a potent small molecule V domain T-cell activating immunoglobulin suppressor (VISTA) inhibitor with IC50 value of 121 nM. MG-V-53 has antitumor activity.

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MG-V-53 Chemical Structure

MG-V-53 Chemical Structure

CAS No. : 920157-23-9

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MG-V-53 Related Antibodies

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Description

MG-V-53 is a potent small molecule V domain T-cell activating immunoglobulin suppressor (VISTA) inhibitor with IC50 value of 121 nM. MG-V-53 has antitumor activity[1].

IC50 & Target

IC50:121 nM (VISTA )
Molecular Weight

369.37

Formula

C20H17F2N3O2
CAS No.
Appearance

Powder

SMILES

FC1C=CC(C2C=CC(OCCNC(CC3C=CC(F)=CC=3)=O)=NN=2)=CC=1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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MG-V-53 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MG-V-53920157-23-9VISTAInhibitorantitumorinhibitorinhibit

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HY-Q25865
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