2. Natural Products
  3. Plants Phenylpropanoids
  4. Rubiaceae Lignans
  5. Hedyotis uncinella Hook. et Arn.
  6. (-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol

(-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol 

Cat. No.: HY-N3745
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(-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol (compound 10) is a lignan isolated from Hedyotis uncinella.

For research use only. We do not sell to patients.

(-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol Chemical Structure

(-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol Chemical Structure

CAS No. : 126253-41-6

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(-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol Related Antibodies

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Description

(-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol (compound 10) is a lignan isolated from Hedyotis uncinella[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 30 μM
Compound: 10
Cytotoxicity against human A549 cells by SRB assay
Cytotoxicity against human A549 cells by SRB assay
[PMID: 26988298]
BV-2 IC50
39.97 μM
Compound: 10
Anti-neuroinflammatory activity in LPS-activated mouse BV2 cells assessed as inhibition of NO production after 24 hrs by Griess assay
Anti-neuroinflammatory activity in LPS-activated mouse BV2 cells assessed as inhibition of NO production after 24 hrs by Griess assay
[PMID: 26988298]
SK-MEL-2 IC50
> 30 μM
Compound: 10
Cytotoxicity against human SK-MEL-2 cells by SRB assay
Cytotoxicity against human SK-MEL-2 cells by SRB assay
[PMID: 26988298]
SK-OV-3 IC50
> 30 μM
Compound: 10
Cytotoxicity against human SKOV3 cells by SRB assay
Cytotoxicity against human SKOV3 cells by SRB assay
[PMID: 26988298]
XF498 IC50
> 30 μM
Compound: 10
Cytotoxicity against human XF498 cells by SRB assay
Cytotoxicity against human XF498 cells by SRB assay
[PMID: 26988298]
Molecular Weight

360.40

Formula

C20H24O6
CAS No.
SMILES

OC[C@@H]1C2=CC(CCCO)=CC(OC)=C2O[C@H]1C3=CC(OC)=C(C=C3)O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(-)-(7R, 8S)-dihydrodehydrodiconiferyl alcohol126253-41-6OthersHedyotis uncinella(7R8S)-Balanophonin8S)-Tomentosanan ALignansInhibitorinhibitorinhibit

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