(-)-β-Peltatin (Synonyms: β-Peltatin)

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(-)-β-Peltatin is an organic heterotetracyclic compound with antitumor activity and phytometabolite effects that are functionally related to α-peltatin.

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(-)-β-Peltatin Chemical Structure

CAS No. : 518-29-6

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Description

(-)-β-Peltatin is an organic heterotetracyclic compound with antitumor activity and phytometabolite effects that are functionally related to α-peltatin^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
BXPC-3	GI₅₀	0.0012 μg/mL Compound: 3	Growth inhibition of human BxPC3 cells measured after 48 hrs by sulforhodamine B assay Growth inhibition of human BxPC3 cells measured after 48 hrs by sulforhodamine B assay	[PMID: 26938998]
DU-145	GI₅₀	0.0021 μg/mL Compound: 3	Growth inhibition of human DU145 cells measured after 48 hrs by sulforhodamine B assay Growth inhibition of human DU145 cells measured after 48 hrs by sulforhodamine B assay	[PMID: 26938998]
HL-60	IC₅₀	0.0052 μg/mL Compound: 11	Cytotoxicity against human HL-60 cells after 72 hrs by MTT assay Cytotoxicity against human HL-60 cells after 72 hrs by MTT assay	[PMID: 10514313]
KM-20L2	GI₅₀	0.0076 μg/mL Compound: 3	Growth inhibition of human KM20L2 cells measured after 48 hrs by sulforhodamine B assay Growth inhibition of human KM20L2 cells measured after 48 hrs by sulforhodamine B assay	[PMID: 26938998]
MCF7	GI₅₀	0.00055 μg/mL Compound: 3	Growth inhibition of human MCF7 cells measured after 48 hrs by sulforhodamine B assay Growth inhibition of human MCF7 cells measured after 48 hrs by sulforhodamine B assay	[PMID: 26938998]
NCI-H460	GI₅₀	0.00077 μg/mL Compound: 3	Growth inhibition of human NCI-H460 cells measured after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-H460 cells measured after 48 hrs by sulforhodamine B assay	[PMID: 26938998]
P388	ED₅₀	0.0031 μg/mL Compound: 3	Growth inhibition of mouse P388 cells measured after 48 hrs by sulforhodamine B assay Growth inhibition of mouse P388 cells measured after 48 hrs by sulforhodamine B assay	[PMID: 26938998]
SF-268	GI₅₀	0.0004 μg/mL Compound: 3	Growth inhibition of human SF268 cells measured after 48 hrs by sulforhodamine B assay Growth inhibition of human SF268 cells measured after 48 hrs by sulforhodamine B assay	[PMID: 26938998]

Molecular Weight

414.41

Formula

C₂₂H₂₂O₈

CAS No.

518-29-6

SMILES

O=C1[C@]2([H])[C@H](C3=CC(OC)=C(C(OC)=C3)OC)C4=CC(OCO5)=C5C(O)=C4C[C@@]2([H])CO1

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Widad M.Kamil, et al. Biosynthesis of the lignans α- and β-peltatin. Phytochemistry Volume 25, Issue 9, 1986, Pages 2089-2092.

(-)-β-Peltatin Related Classifications

Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(-)-β-Peltatin518-29-6β-PeltatinOthersheterotetracyclic compoundantitumorphytometaboliteα-peltatinInhibitorinhibitorinhibit

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