2. Anti-infection
  3. SARS-CoV
  4. MK-7845

MK-7845 is a reversible covalent SARS-CoV-2 3CL protease inhibitor with an IC50 of 8.7 nM.

For research use only. We do not sell to patients.

MK-7845 Chemical Structure

MK-7845 Chemical Structure

CAS No. : 2952554-69-5

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MK-7845 Related Antibodies

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Description

MK-7845 is a reversible covalent SARS-CoV-2 3CL protease inhibitor with an IC50 of 8.7 nM[1].

IC50 & Target

IC50: 8.7 nM (3CLPro)[1]
Molecular Weight

516.58

Formula

C24H38F2N4O6
CAS No.
SMILES

CNC(C([C@@H](NC([C@@H]1[C@H]2CCC[C@H]2CN1C([C@H](C(C)(C)C)NC(OC)=O)=O)=O)CCC(F)(F)C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MK-7845 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MK-78452952554-69-5MK7845MK 7845SARS-CoVSARS coronavirusSARS-CoV-2 3CL Protease Inhibitorreversible covalentdifluorobutyl substituentInhibitorinhibitorinhibit

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