MRS4620

Cat. No.: HY-144072: FAQs
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MRS4620 is a potent CD73 inhibitor, with a K_i of 0.436 nM. MRS4620 can be use for the research of cancer immunoresearch.

For research use only. We do not sell to patients.

MRS4620 Chemical Structure

CAS No. : 2411665-73-9

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Description	MRS4620 is a potent CD73 inhibitor, with a K_i of 0.436 nM. MRS4620 can be use for the research of cancer immunoresearch^[1].
Molecular Weight	647.25
Formula	C₁₈H₂₄IN₃O₁₁P₂
CAS No.	2411665-73-9
SMILES	O[C@H]1[C@@](N2C(N(/C(C=C2)=N\OCC3=CC=C(C=C3)I)C)=O)([H])O[C@@H]([C@H]1O)COP(CP(O)(O)=O)(O)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (266 KB) Handling Instructions (2659 KB)
References	[1]. Scortichini M, et, al. Structure-Activity Relationship of 3-Methylcytidine-5'-α,β-methylenediphosphates as CD73 Inhibitors. J Med Chem. 2022 Feb 10;65(3):2409-2433. [Content Brief]

MRS4620 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MRS46202411665-73-9MRS 4620MRS-4620CD73ecto-5′-nucleotidase, NT5Ecancer immunotherapyInhibitorinhibitorinhibit

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MRS4620

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