2. Anti-infection
  3. Bacterial
  4. Mtb-cyt-bd oxidase-IN-7

Mtb-cyt-bd oxidase-IN-7 is a cytochrome bd terminal oxidase (Cyt-bd) inhibitor with a Kd value of 4.17 μM. Mtb-cyt-bd oxidase-IN-7 shows anti-tuberculosis activities.

For research use only. We do not sell to patients.

Mtb-cyt-bd oxidase-IN-7 Chemical Structure

Mtb-cyt-bd oxidase-IN-7 Chemical Structure

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Mtb-cyt-bd oxidase-IN-7 Related Antibodies

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Description

Mtb-cyt-bd oxidase-IN-7 is a cytochrome bd terminal oxidase (Cyt-bd) inhibitor with a Kd value of 4.17 μM. Mtb-cyt-bd oxidase-IN-7 shows anti-tuberculosis activities[1].

In Vitro

Mtb-cyt-bd oxidase-IN-7 (compound 8d) is a 1-hydroxy-2-methylquinolin-4(1H)-one derivative. Mtb-cyt-bd oxidase-IN-7 inhibits the growth of the cytochrome bcc-aa3 oxidase (Cyt-bcc) knock-out strain (ΔqcrCAB, Cyt-bd+) with a MIC value of 6.25 μM. The combination of Mtb-cyt-bd oxidase-IN-7 with the Cyt-bcc inhibitor Q203 completely inhibited oxygen consumption of the wild-type strain and the inverted-membrane vesicles expressing M. tuberculosis Cyt-bd (ΔcydAB::MtbCydAB+)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Mtb-cyt-bd oxidase-IN-7 Related Antibodies
Molecular Weight

333.30

Formula

C18H14F3NO2
SMILES

CC1=C(C(C2=CC=CC=C2N1O)=O)CC3=CC=C(C=C3)C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Mtb-cyt-bd oxidase-IN-7 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mtb-cyt-bd oxidase-IN-7BacterialCyt-bccCyt-bdMycobacterium tuberculosisanti-tuberculosis activitiesInhibitorinhibitorinhibit

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