786-0
|
GI50 |
0.415 μM
Compound: 5, NSC-747259
|
Growth inhibition of human 786-0 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human 786-0 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
A498
|
GI50 |
1.82 μM
Compound: 5, NSC-747259
|
Growth inhibition of human A498 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human A498 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
A549
|
GI50 |
1.9 μM
Compound: 5, NSC-747259
|
Growth inhibition of human A549 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human A549 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
ACHN
|
GI50 |
0.63 μM
Compound: 5, NSC-747259
|
Growth inhibition of human ACHN cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human ACHN cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
BT-549
|
GI50 |
0.421 μM
Compound: 5, NSC-747259
|
Growth inhibition of human BT549 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human BT549 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
CCRF-CEM
|
GI50 |
0.19 μM
Compound: 5, NSC-747259
|
Growth inhibition of human CCRF-CEM cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human CCRF-CEM cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
COLO 205
|
GI50 |
0.292 μM
Compound: 5, NSC-747259
|
Growth inhibition of human COLO205 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human COLO205 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
DU-145
|
GI50 |
0.407 μM
Compound: 5, NSC-747259
|
Growth inhibition of human DU145 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human DU145 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
EKVX
|
GI50 |
0.215 μM
Compound: 5, NSC-747259
|
Growth inhibition of human EKVX cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human EKVX cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
HCC 2998
|
GI50 |
0.425 μM
Compound: 5, NSC-747259
|
Growth inhibition of human HCC2998 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human HCC2998 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
HCT-116
|
GI50 |
0.319 μM
Compound: 5, NSC-747259
|
Growth inhibition of human HCT116 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human HCT116 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
HCT-15
|
GI50 |
0.993 μM
Compound: 5, NSC-747259
|
Growth inhibition of human HCT15 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human HCT15 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
HL-60(TB)
|
GI50 |
0.173 μM
Compound: 5, NSC-747259
|
Growth inhibition of human HL-60(TB) cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human HL-60(TB) cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
HOP-62
|
GI50 |
0.787 μM
Compound: 5, NSC-747259
|
Growth inhibition of human HOP62 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human HOP62 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
HOP-92
|
GI50 |
0.206 μM
Compound: 5, NSC-747259
|
Growth inhibition of human HOP92 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human HOP92 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
Hs-578T
|
GI50 |
0.417 μM
Compound: 5, NSC-747259
|
Growth inhibition of human Hs 578T cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human Hs 578T cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
HT-29
|
GI50 |
0.305 μM
Compound: 5, NSC-747259
|
Growth inhibition of human HT-29 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human HT-29 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
IGROV-1
|
GI50 |
0.388 μM
Compound: 5, NSC-747259
|
Growth inhibition of human IGROV1 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human IGROV1 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
K562
|
GI50 |
0.186 μM
Compound: 5, NSC-747259
|
Growth inhibition of human K562 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human K562 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
KM12
|
GI50 |
0.31 μM
Compound: 5, NSC-747259
|
Growth inhibition of human KM12 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human KM12 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
LOX IMVI
|
GI50 |
0.192 μM
Compound: 5, NSC-747259
|
Growth inhibition of human LOXIMVI cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human LOXIMVI cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
M14
|
GI50 |
0.453 μM
Compound: 5, NSC-747259
|
Growth inhibition of human M14 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human M14 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
Malme-3M
|
GI50 |
0.29 μM
Compound: 5, NSC-747259
|
Growth inhibition of human MALME-3M cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human MALME-3M cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
MCF7
|
GI50 |
0.317 μM
Compound: 5, NSC-747259
|
Growth inhibition of human MCF7 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human MCF7 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
MDA-MB-231
|
GI50 |
0.345 μM
Compound: 5, NSC-747259
|
Growth inhibition of human MDA-MB-231 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human MDA-MB-231 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
MDA-MB-435
|
GI50 |
0.335 μM
Compound: 5, NSC-747259
|
Growth inhibition of human MDA-MB-435 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human MDA-MB-435 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
MDA-MB-468
|
GI50 |
0.119 μM
Compound: 5, NSC-747259
|
Growth inhibition of human MDA-MB-468 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human MDA-MB-468 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
MOLT-4
|
GI50 |
0.324 μM
Compound: 5, NSC-747259
|
Growth inhibition of human MOLT4 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human MOLT4 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
NCI/ADR-RES
|
GI50 |
1.68 μM
Compound: 5, NSC-747259
|
Growth inhibition of human NCI/ADR-RES cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human NCI/ADR-RES cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
NCI-H226
|
GI50 |
0.478 μM
Compound: 5, NSC-747259
|
Growth inhibition of human NCI-H226 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human NCI-H226 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
NCI-H23
|
GI50 |
0.308 μM
Compound: 5, NSC-747259
|
Growth inhibition of human NCI-H23 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human NCI-H23 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
NCI-H322M
|
GI50 |
1.81 μM
Compound: 5, NSC-747259
|
Growth inhibition of human NCI-H322M cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human NCI-H322M cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
NCI-H460
|
GI50 |
0.362 μM
Compound: 5, NSC-747259
|
Growth inhibition of human NCI-H460 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human NCI-H460 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
NCI-H522
|
GI50 |
0.287 μM
Compound: 5, NSC-747259
|
Growth inhibition of human NCI-H522 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human NCI-H522 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
OVCAR-3
|
GI50 |
0.315 μM
Compound: 5, NSC-747259
|
Growth inhibition of human OVCAR-3 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human OVCAR-3 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
OVCAR-4
|
GI50 |
0.309 μM
Compound: 5, NSC-747259
|
Growth inhibition of human OVCAR4 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human OVCAR4 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
OVCAR-5
|
GI50 |
1.24 μM
Compound: 5, NSC-747259
|
Growth inhibition of human OVCAR5 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human OVCAR5 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
OVCAR-8
|
GI50 |
0.468 μM
Compound: 5, NSC-747259
|
Growth inhibition of human OVCAR8 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human OVCAR8 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
PC-3
|
GI50 |
0.282 μM
Compound: 5, NSC-747259
|
Growth inhibition of human PC3 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human PC3 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
RPMI-8226
|
GI50 |
0.046 μM
Compound: 5, NSC-747259
|
Growth inhibition of human RPMI8226 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human RPMI8226 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
RXF 393
|
GI50 |
0.464 μM
Compound: 5, NSC-747259
|
Growth inhibition of human RFX393 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human RFX393 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
SF-268
|
GI50 |
0.493 μM
Compound: 5, NSC-747259
|
Growth inhibition of human SF268 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human SF268 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
SF-295
|
GI50 |
0.333 μM
Compound: 5, NSC-747259
|
Growth inhibition of human SF295 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human SF295 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
SF-539
|
GI50 |
0.514 μM
Compound: 5, NSC-747259
|
Growth inhibition of human SF539 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human SF539 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
SK-MEL-2
|
GI50 |
0.356 μM
Compound: 5, NSC-747259
|
Growth inhibition of human SK-MEL-2 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human SK-MEL-2 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
SK-MEL-28
|
GI50 |
0.71 μM
Compound: 5, NSC-747259
|
Growth inhibition of human SK-MEL-28 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human SK-MEL-28 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
SK-MEL-5
|
GI50 |
0.177 μM
Compound: 5, NSC-747259
|
Growth inhibition of human SK-MEL-5 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human SK-MEL-5 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
SK-OV-3
|
GI50 |
0.565 μM
Compound: 5, NSC-747259
|
Growth inhibition of human SKOV3 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human SKOV3 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
SN12C
|
GI50 |
0.367 μM
Compound: 5, NSC-747259
|
Growth inhibition of human SN12C cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human SN12C cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
SNB-19
|
GI50 |
0.587 μM
Compound: 5, NSC-747259
|
Growth inhibition of human SNB19 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human SNB19 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
SNB-75
|
GI50 |
0.336 μM
Compound: 5, NSC-747259
|
Growth inhibition of human SNB75 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human SNB75 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
SR
|
GI50 |
0.162 μM
Compound: 5, NSC-747259
|
Growth inhibition of human SR cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human SR cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
SW-620
|
GI50 |
0.378 μM
Compound: 5, NSC-747259
|
Growth inhibition of human SW620 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human SW620 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
T47D
|
GI50 |
0.428 μM
Compound: 5, NSC-747259
|
Growth inhibition of human T47D cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human T47D cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
TK-10
|
GI50 |
0.503 μM
Compound: 5, NSC-747259
|
Growth inhibition of human TK10 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human TK10 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
U-251
|
GI50 |
0.334 μM
Compound: 5, NSC-747259
|
Growth inhibition of human U251 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human U251 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
UACC-257
|
GI50 |
0.411 μM
Compound: 5, NSC-747259
|
Growth inhibition of human UACC257 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human UACC257 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
UACC-62
|
GI50 |
0.335 μM
Compound: 5, NSC-747259
|
Growth inhibition of human UACC62 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human UACC62 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|
UO-31
|
GI50 |
0.686 μM
Compound: 5, NSC-747259
|
Growth inhibition of human UO31 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
Growth inhibition of human UO31 cells assessed as drug level required for 50% reduction in net protein increase by SRB assay relative to control
|
[PMID: 19615902]
|