MTvkPABC-P5 TFA

Cat. No.: HY-156693A: FAQs
Data Sheet Handling Instructions Technical Support

MTvkPABC-P5d TFA, a TLR7 agonist, is an immune stimulant. MTvkPABC-P5d TFA can be used for synthesis of immune-stimulating antibody conjugates (ISACs).

For research use only. We do not sell to patients.

MTvkPABC-P5 TFA Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of MTvkPABC-P5 TFA:

MTvkPABC-P5 Get quote

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View All Toll-like Receptor (TLR) Isoform Specific Products:

View All Isoforms

TLR3 TLR8 TLR9 TLR2 TLR4 TLR7 TLR1 TLR6

Biological Activity
Purity & Documentation
References
Customer Review

Description

MTvkPABC-P5d TFA, a TLR7 agonist, is an immune stimulant. MTvkPABC-P5d TFA can be used for synthesis of immune-stimulating antibody conjugates (ISACs)^[1].

IC₅₀ & Target^[1]

TLR7

Molecular Weight

1190.22

Formula

C₅₄H₇₄F₃N₁₁O₁₆

Appearance

Solid

SMILES

O=C(N(CC1=CC(OC)=C(CN2C3=NC(OCC)=NC(N)=C3N=C2O)C=C1)CC(C)(O)C)OCC(C=C4)=CC=C4NC([C@H](CCCCN)NC([C@H](C(C)C)NC(CCOCCOCCOCCN5C(C=CC5=O)=O)=O)=O)=O.OC(C(F)(F)F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Graham Garnett, et al. Optimization of purine-based TLR7 agonists as payloads for immune-stimulating antibody conjugates (ISACs). J Immunother Cancer. Volume 10, Issue Suppl 2.

MTvkPABC-P5 TFA Related Classifications

Inflammation/Immunology

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MTvkPABC-P5Toll-like Receptor (TLR)ISACimmune stimulantTLR7 agonistInhibitorinhibitorinhibit

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