Myricananin A

Cat. No.: HY-N3226: FAQs
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Myricananin A is a colorless needle that has inhibitory effect on iNOS.

For research use only. We do not sell to patients.

Myricananin A Chemical Structure

CAS No. : 1079941-35-7

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nNOS iNOS eNOS

Biological Activity
Purity & Documentation
References
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Description

Myricananin A is a colorless needle that has inhibitory effect on iNOS^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
Macrophage	IC₅₀	45.32 μM Compound: 1, Myricananin A	Inhibition of LPS-stimulated nitric oxide production in BALB/c mouse macrophages after 20 hrs by Griess assay relative to control Inhibition of LPS-stimulated nitric oxide production in BALB/c mouse macrophages after 20 hrs by Griess assay relative to control	[PMID: 18723353]

In Vitro

Myricananin A (0-100 µM; 24 h) inhibits the expression of iNOS in LPS-activated macrophages with dose-dependent manner^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis^[1]

Cell Line:	LPS-activated macrophages.
Concentration:	0, 1, 3, 10, 30 and 100 µM.
Incubation Time:	24 h.
Result:	Inhibited the expression of iNOS.

Molecular Weight

344.40

Formula

C₂₀H₂₄O₅

CAS No.

1079941-35-7

SMILES

OC1=C2C3=C(O)C=CC(C[C@@H]([C@H](CCCCC(C=C1OC)=C2)O)O)=C3

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wang J, et al. Cyclic diarylheptanoids from Myrica nana inhibiting nitric oxide release. Bioorg Med Chem. 2008 Sep 15;16(18):8510-5. [Content Brief]

Myricananin A Related Classifications

Inflammation/Immunology

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Myricananin A1079941-35-7NO SynthaseNitric oxide synthasesNOSLPSMacrophagesInhibitorinhibitorinhibit

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