Search Result
Results for "
n-2-aminoethyl-2-naphthalen-1-yl-acetamide-d4
" in MedChemExpress (MCE) Product Catalog:
16
Biochemical Assay Reagents
1
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-Y0946
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Biochemical Assay Reagents
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Inflammation/Immunology
Cancer
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Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity. Acetamide derivatives may has antioxidant activity and potential anti-inflammatory activity. Acetamide holds promise for research in the fields of anti-inflammatory and cancer studies .
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- HY-Y0946S
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Isotope-Labeled Compounds
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Cancer
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Acetamide- 15N is the 15N-labeled Acetamide. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity[1][2].
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- HY-W016876
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Biochemical Assay Reagents
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Others
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2-(Naphthalen-1-yl)ethanol is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-W040209
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α-NPO
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Fluorescent Dye
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Others
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2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye. 2-(Naphthalen-1-yl)-5-phenyloxazole has a nitrogen atom in its structure that can interfere with the nitrogen content from the amination step .
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- HY-W009724
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2-APB
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Calcium Channel
TRP Channel
CRAC Channel
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Cardiovascular Disease
Inflammation/Immunology
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2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R). 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca 2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). Additionally, 2-Aminoethyl diphenylborinate has inhibitory effects on vasospasm. At high concentrations, it exhibits specific anti-inflammatory and antioxidant effects in neural tissue .
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- HY-W016187
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2-Naphthylacetic acid
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Biochemical Assay Reagents
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Others
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2-(Naphthalen-2-yl)acetic acid (2-Naphthylacetic acid), a plant growth regulator, is a 3-Indoleacetic acid (HY-18569) antagonist .
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- HY-157360
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Biochemical Assay Reagents
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Others
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Acetamide Agar is a solid culture media for non-fermenting bacteria. Acetamide Agar helps differentiate P. acidovorans from other non-sugar-soluble or weakly sugar-soluble Pseudomonas species. Acetamide Agar can be used to test the ability of microorganisms such as Pseudomonas aeruginosa to utilize acetamide through deamination .
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- HY-Y0946R
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Biochemical Assay Reagents
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Inflammation/Immunology
Cancer
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Acetamide (Standard) is the analytical standard of Acetamide. This product is intended for research and analytical applications. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity. Acetamide derivatives may has antioxidant activity and potential anti-inflammatory activity. Acetamide holds promise for research in the fields of anti-inflammatory and cancer studies .
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- HY-W087942
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Biochemical Assay Reagents
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Others
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Sodium naphthalen-1-yl phosphate, hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W039763
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- HY-W016784
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Endogenous Metabolite
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Others
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Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class .
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- HY-W398806
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PROTAC Linkers
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Cancer
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(2-Aminoethyl)carbamic acid is a PROTAC linker that belongs to the PEG class. (2-Aminoethyl)carbamic acid can be used to synthesize QS-57 (HY-169081) .
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- HY-W006371
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- HY-W141704
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Drug Intermediate
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Others
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N-(3-Aminopropyl)acetamide is the building block. N-(3-Aminopropyl)acetamide could be used for synthesis of Polyfluorosulfonamido amine, which is the material for surfactants, electronics elements, pharmaceutical- and pesticide intermediates .
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- HY-W009197
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- HY-W008489
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-
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- HY-W011322
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- HY-W098764
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ADC Linker
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Others
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Allyl (2-aminoethyl)carbamate hydrochloride is a cleavable linker.
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- HY-145735
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- HY-101403
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- HY-140096
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ADC Linker
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Cancer
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Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-117409
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ADC Linker
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Cancer
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Aminoethyl-SS-ethylalcohol is a glutathione cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-165859
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- HY-47858
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-
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- HY-W068119A
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2-Maleimidoethylamine hydrochloride
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Biochemical Assay Reagents
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Cancer
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N-(2-Aminoethyl)maleimide (2-Maleimidoethylamine) hydrochloride is a cross-linker. N-(2-Aminoethyl)maleimide hydrochloride can be used to prepare MMP-2 sensitive nanosystem, and for cancer research .
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- HY-W127804
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- HY-165929
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- HY-165935
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- HY-W164451
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Fungal
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Infection
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N-(2-hydroxy-2-phenylethyl)acetamide is isolated from the solid rice cultures of the endophytic fungus Diaporthe eucalyptorum KY-9. N-(2-hydroxy-2-phenylethyl)acetamide exhibits antifungal activities against Alternaria solani .
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- HY-153263
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Drug-Linker Conjugates for ADC
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Cancer
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(Aminooxy)acetamide-Val-Cit-PAB-MMAE (MMAE 5) is an intermediate used in the synthetic preparation of drug-linker conjugates for ADC. (Aminooxy)acetamide-Val-Cit-PAB-MMAE is conjugated to polyamide via oxime bond formation to form MMAE polyamide conjugate. Then MMAE polyamide conjugate can be conjugated to Trastuzumab, to make ADC .
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- HY-W012883
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- HY-159162A
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7CPT TFA
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Others
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Others
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7-(2-Aminoethyl)camptothecin TFA (7CPT TFA) is the TFA salt form of Camptothecin (HY-16560) derivative 7-(2-Aminoethyl)camptothecin (HY-159162). 7-(2-Aminoethyl)camptothecin TFA can be used for synthesis of conjugate with triple helix-forming oligonucleotides (TFOs) and camptothecin (CPT). The TFO-CPT conjugate is used for DNA cleavage .
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- HY-W008596
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- HY-W699317
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- HY-W067445
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4-Acetamidobenzaldehyde
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Biochemical Assay Reagents
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Others
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N-(4-Formylphenyl)acetamide (4-Acetamidobenzaldehyde) is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-159162
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7CPT
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Others
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Others
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7-(2-Aminoethyl)camptothecin (7CPT) is a derivative of camptothecin that can be used to prepare TFO-CPT conjugates .
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- HY-D0131
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Fluorescent Dye
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Others
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2-Methoxy-2-(naphthalen-2-yl)acetonitrile is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D0137
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Fluorescent Dye
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Others
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2-(Benzyloxy)-2-(naphthalen-2-yl)acetonitrile is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D0138
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Fluorescent Dye
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Others
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2-(Naphthalen-2-yl)-2-(pentyloxy)acetonitrile is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-161493
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- HY-161525
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Biochemical Assay Reagents
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Inflammation/Immunology
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1-(2-Aminoethyl)-1H-pyrazol-4-ylphosphonic acid linker/BSA is the conjugate of 1-(2-Aminoethyl)-1H-pyrazol-4-ylphosphonic acid linker (1-(2-氨基乙基)-1H-吡唑-4-基膦酸连接子) and bovine serum albumin (BSA). By conjugating the antigen with a protein adjuvant, it enhances the production of antigen-specific antibodies in vaccine models. The conjugate does not affect protein folding or disrupt key epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.
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- HY-101424
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Fungal
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Infection
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2-Chloro-N-(2-methyl-4-bromophenyl)acetamide is an antifungal compound .
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- HY-106947
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Endogenous Metabolite
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Metabolic Disease
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SY-640 is an Acetamide derivative and has potent hepatoprotective effect. SY-640 reduces Propionibacterium acnes and Lipopolysaccharide-induced liver injury in mice .
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- HY-100138
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- HY-152727
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Nucleoside Antimetabolite/Analog
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Others
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9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(naphthalen-1-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-D1524
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1,8-EDNAS
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Fluorescent Dye
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Others
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N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid is a fluorescent reagent .
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- HY-15254
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25-Hydroxy Vitamin D3 3,3’-Aminopropyl Ether
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VD/VDR
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Metabolic Disease
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3-O-(2-Aminoethyl)-25-hydroxyvitamin D3 is a Vitamin D3 derivative.
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- HY-112106A
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DA-6 citrate; 2-Diethylaminoethyl hexanoate citrate
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Others
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Others
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Diethyl aminoethyl hexanoate citrate is a compound that is widely used as a plant growth regulator.
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- HY-129907
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2-aminoethyl methylphosphonate
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GABA Receptor
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Neurological Disease
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2-AEMP (2-Aminoethyl methylphosphonate) is an anti-GABA(A)-ρ1 receptor compound with antagonist activity. 2-AEMP exhibits competitive inhibition compared to TPMPA with an IC(50) value of 18 μM, compared to 7 μM for TPMPA. The release rate of inhibition at termination of 2-AEMP is significantly higher than that of TPMPA. The preincubation time required for the onset of inhibition of 2-AEMP is much shorter than that of TPMPA. Some analogs of 2-AEMP, especially those with benzyl or n-butyl substituents, show lower potency in terms of biological activity .
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- HY-W089645
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N-Methyl-n-trimethylsilyltrifluoroacetamide
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Others
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Metabolic Disease
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2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide (N-Methyl-n-trimethylsilyltrifluoroacetamide) is an ester product.
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- HY-140960
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PROTAC Linkers
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Cancer
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DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside, MW 2000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W101718
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Isotope-Labeled Compounds
ADC Linker
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Cancer
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Fmoc-N-(2-Boc-aminoethyl)-Gly-OH is a Fmoc-protected glycine derivative that can be used in antibody agent coupling (ADC) synthesis. ADC consists of antibodies that are linked to ADC cytotoxins via ADC junctions[1].
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- HY-161491
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Fluorescent Dye
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Others
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1-(2-Aminoethyl)-1H-pyrazol-4-ylphosphonic acid-linker/OVA is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-D0532
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Fluorescent Dye
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Others
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N-[5-2-[Azo]phenyl]acetamide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-W053701
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Amino Acid Derivatives
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Others
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N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((5-(dimethylamino)naphthalen-1-yl)sulfonyl)-L-lysine is a lysine derivative .
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- HY-159772
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PROTAC Linkers
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Cancer
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1-(4-(2-Aminoethyl)piperidin-1-yl)-2-azidoethan-1-one is (HY-169133) PROTACT's Linker. 1- (4- (2-aminoEyl) Piperidin-YL) -2-Azidoethan-One can be used to synthesize PROTACT molecules .
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- HY-402277
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Biochemical Assay Reagents
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Others
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2-[[[4-(Acetylamino)phenyl]sulfonyl][(4-fluorophenyl)methyl]amino]-N-(9-ethyl-9H-carbazol-3-yl)acetamide is a biological molecule.
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- HY-136205
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Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide
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TRP Channel
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Infection
Inflammation/Immunology
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IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection . IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling . IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D1524A
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1,8-EDNAS sodium
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Fluorescent Dye
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Others
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N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid sodium (1,8-EDNAS sodium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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- HY-150408
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AUTACs
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Cancer
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FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a linker of AUTAC4. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells .
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- HY-W002570
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Biochemical Assay Reagents
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Others
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Naphthalen-2-boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-109573
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Phospholipase
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Cancer
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hnps-PLA-IN-1 (compound 5aa), a indole-3-acetamide, is a hnps-PLA2 inhibitor (IC50=0.124 μM) .
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- HY-18594
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Others
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Others
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NSC-41589 is an N-[2-(methylsulfanyl) phenyl]acetamide.
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- HY-144426
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Influenza Virus
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Infection
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Neuraminidase-IN-6 (Compound 5c) is a potent inhibitor of neuraminidase with an IC50 of 0.11 μM. Neuraminidase-IN-6 is a 1,3,4-triazole-3-acetamide derivative. Neuraminidase (NA) is an ideal target for the development of anti-influenza agents .
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- HY-157329
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Endonuclease
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Inflammation/Immunology
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AD16 (Acetamide) is a LINE-1 retrotransposon endonuclease inhibitor with the IC50 of 4.7 μM. AD16 (Acetamide) reduce LINE-1 retrotransposition, L1-induced DNA damage, and inflammation reinforced by L1 in senescent cells .
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- HY-169081
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PROTACs
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Others
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QS-57 is a PROTAC targeting BRD4. QS-57 can be used as a 14-3-3 molecular glue. (Red: EN171 (HY-W1005067), black: (2-Aminoethyl) carbamic acid (HY-W398806), Blue: JQ-1 (carboxylic acid) (HY-78695)) .
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- HY-W012568
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Others
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Others
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1-Methoxynaphthalene is used as the substrate to investigate the activity of cytochrome c peroxidase (CcP). 1-Methoxynaphthalene also can be used to synthesize prenyl naphthalen-ols .
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- HY-124175
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Others
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Endocrinology
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16-Phenoxy prostaglandin F2α ethyl amide is a metabolically stable PGF2α analogue containing a acetamide structure .
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- HY-40174A
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Biochemical Assay Reagents
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Others
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tert-Butyl (2-aminoethyl)(methyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-47876
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Others
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Others
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2-(((Benzo[d][1,3]dioxol-5-ylmethylene)amino)oxy)-N-(m-tolyl)acetamide is an active molecule.
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- HY-120369
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FAAH
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Neurological Disease
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URB532 is an inhibitor for fatty acid amide hydrolase (FAAH) with an IC50 of 396 nM. URB532 increases levels of arachidonic acid acetamide (AEA), palmitoylethanolamide (PEA), and oleamide (OEA) in the rat brain, and exhibits anxiolytic and analgesic effects .
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- HY-B2132
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3-(2-aminoethyl)indole~2-(3-Indolyl)ethylamine
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Endogenous Metabolite
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Others
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Tryptamine is a monoamine alkaloid, similar to other trace amines, is believed to play a role as a neuromodulator or neurotransmitter.
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- HY-W013166
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N-Biotinylaminoethyl methanethiosulfonate
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Others
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Others
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MTSEA-biotin is a biotin-conjugated 2-aminoethyl-methanethiosulfonate that can be used to specifically label modified nucleosides. MTSEA-biotin binds 4-thiouridine (s4U) to visualize newly transcribed tRNA in Saccharomyces cerevisiae cells .
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- HY-146373
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Bacterial
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Infection
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The minimum inhibitory concentration (MIC) of a new 2- (quinoline-4-methoxy) acetamide antituberculotic agent against the reference strain of Mycobacterium tuberculosis H37Rv was as low as 0.3 μ M. It also inhibited the growth of Mycobacterium tuberculosis in the macrophage model of tuberculosis infection.
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- HY-103247B
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Angiotensin Receptor
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Cardiovascular Disease
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EMD-66684 potassium salt is a non-peptide angiotensin II receptor antagonist that demonstrates significant antihypertensive effects in spontaneously hypertensive rats. EMD-66684 potassium salt exhibits nanomolar affinity for angiotensin II receptors, comparable to losartan in potency. EMD-66684 potassium salt shows increased activity when modified with acetamides, leading to superior blood pressure reduction.
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- HY-P4154
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ALM-488
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Fluorescent Dye
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Neurological Disease
Cancer
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Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .
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- HY-P3815
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Casein Kinase
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Others
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Casein Kinase 2 Substrate Peptide is a common CK2 substrate peptide. Casein Kinase 2 Substrate Peptide is synthesized with its C-terminus conjugated to 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid (EDANS). Casein Kinase 2 Substrate Peptide can be used for protein kinase CK2 activity determination .
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- HY-P1103A
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CXCR
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Cancer
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CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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- HY-P1103
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CXCR
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Cancer
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CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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- HY-14988
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Bacterial
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Infection
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I-A09 and its derivatives, specifically 1,2,3-triazole-adamantylacetamide hybrids (5a–u), exhibit significant antitubercular activity. These hybrids were synthesized using copper-catalyzed click chemistry, combining bioactive fragments from antitubercular I-A09 and substituted adamantyl urea. The compound N-(1-adamantyl)-2-azido acetamide was reacted with various alkyl/aryl acetylenes to produce new analogues. Among them, N-(1-adamantan-1-yl)-2-(4-(phenanthren-2-yl)-1H-1,2,3-triazol-1-yl)acetamide (5t) showed the most promise with a minimum inhibitory concentration (MIC) of 3.12 μg/mL against Mycobacterium tuberculosis H37Rv, and a selectivity index greater than 15 .
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- HY-P2231A
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MEDI0382 acetate
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GCGR
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Metabolic Disease
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Cotadutide (MEDI0382) acetate is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide acetate exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide acetate can be used in the research of obesity and type 2 diabetes (T2D) .
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- HY-W073762
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Biochemical Assay Reagents
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Cancer
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FBnG is a component of non-ribosomal peptide synthetase/polyketide synthase (NRPS/PKS), which is associated with the biosynthesis of fabrubactin (FBN). FBnG can be used for synthesis of AUTAC4 as part of FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 (HY-150408) .
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- HY-P2075
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Renin
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Endocrinology
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EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .
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- HY-P0009A
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- HY-P0009B
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- HY-P2231
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MEDI0382
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GCGR
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Metabolic Disease
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Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D) .
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- HY-P10472
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GnRH Receptor
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Endocrinology
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Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
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- HY-P10341
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GCGR
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Metabolic Disease
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ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .
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- HY-131374
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CXCR
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Cancer
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TN14003 is a CXCR4 inhibitor. TN14003 has antitumor activity .
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-
- HY-169082
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E3 Ligase Ligand-Linker Conjugates
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Cancer
|
JQ-1 (carboxylic acid)-NH-C2-NH-COOH is a conjugate of E3 ligase ligand and linker (E3 Ligase Ligand-Linker Conjugates), which is composed of JQ-1 carboxylic acid (HY-78695) and the corresponding linker: (2-Aminoethyl)carbamic acid (HY-W398806). JQ-1 (carboxylic acid)-NH-C2-NH-COOH can be used as a Cereblon ligand to recruit CRBN protein and as a key intermediate for the synthesis of complete PROTACs molecules .
|
-
- HY-P1321
-
1229U91; GW1229
|
Neuropeptide Y Receptor
|
Neurological Disease
|
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
|
-
- HY-P1321A
-
1229U91 TFA; GW1229 TFA
|
Neuropeptide Y Receptor
|
Neurological Disease
|
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
|
-
- HY-P3066
-
d(CH2)5Tyr(Et)VAVP
|
Vasopressin Receptor
|
Metabolic Disease
|
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
|
-
- HY-P4146
-
BI 456906
|
GLP Receptor
GCGR
|
Metabolic Disease
|
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
|
-
- HY-P4146A
-
BI 456906 TFA
|
GLP Receptor
GCGR
|
Metabolic Disease
|
Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-W040209
-
α-NPO
|
Fluorescent Dyes/Probes
|
2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye. 2-(Naphthalen-1-yl)-5-phenyloxazole has a nitrogen atom in its structure that can interfere with the nitrogen content from the amination step .
|
-
- HY-D0131
-
|
Dyes
|
2-Methoxy-2-(naphthalen-2-yl)acetonitrile is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D0137
-
|
Dyes
|
2-(Benzyloxy)-2-(naphthalen-2-yl)acetonitrile is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D0138
-
|
Dyes
|
2-(Naphthalen-2-yl)-2-(pentyloxy)acetonitrile is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D1524
-
-
- HY-D0532
-
|
Dyes
|
N-[5-2-[Azo]phenyl]acetamide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-D1524A
-
1,8-EDNAS sodium
|
Fluorescent Dyes/Probes
|
N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid sodium (1,8-EDNAS sodium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
Cat. No. |
Product Name |
Type |
-
- HY-W016876
-
|
Biochemical Assay Reagents
|
2-(Naphthalen-1-yl)ethanol is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-W016187
-
2-Naphthylacetic acid
|
Biochemical Assay Reagents
|
2-(Naphthalen-2-yl)acetic acid (2-Naphthylacetic acid), a plant growth regulator, is a 3-Indoleacetic acid (HY-18569) antagonist .
|
-
- HY-W068119A
-
2-Maleimidoethylamine hydrochloride
|
Biochemical Assay Reagents
|
N-(2-Aminoethyl)maleimide (2-Maleimidoethylamine) hydrochloride is a cross-linker. N-(2-Aminoethyl)maleimide hydrochloride can be used to prepare MMP-2 sensitive nanosystem, and for cancer research .
|
-
- HY-157360
-
|
Microbial Culture
|
Acetamide Agar is a solid culture media for non-fermenting bacteria. Acetamide Agar helps differentiate P. acidovorans from other non-sugar-soluble or weakly sugar-soluble Pseudomonas species. Acetamide Agar can be used to test the ability of microorganisms such as Pseudomonas aeruginosa to utilize acetamide through deamination .
|
-
- HY-W087942
-
|
Biochemical Assay Reagents
|
Sodium naphthalen-1-yl phosphate, hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127804
-
|
Chelators
|
Tetraacetoxymethyl bis(2-aminoethyl) ether N,N,N',N'-tetraacetic acid is a biochemical reagent.
|
-
- HY-W008596
-
|
Co-solvents
|
2,2,2-Trifluoro-N-(6-hydroxyhexyl)acetamide is a biochemical reagent.
|
-
- HY-W699317
-
ADTNB
|
Cell Assay Reagents
|
5-(2-Aminoethyl)dithio-2-nitrobenzoic acid (ADTNB) is a biochemical reagent.
|
-
- HY-W067445
-
4-Acetamidobenzaldehyde
|
Biochemical Assay Reagents
|
N-(4-Formylphenyl)acetamide (4-Acetamidobenzaldehyde) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-161493
-
|
Biochemical Assay Reagents
|
1-(2-Aminoethyl)-1H-pyrazol-4-ylphosphonic acid/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-161525
-
|
Biochemical Assay Reagents
|
1-(2-Aminoethyl)-1H-pyrazol-4-ylphosphonic acid linker/BSA is the conjugate of 1-(2-Aminoethyl)-1H-pyrazol-4-ylphosphonic acid linker (1-(2-氨基乙基)-1H-吡唑-4-基膦酸连接子) and bovine serum albumin (BSA). By conjugating the antigen with a protein adjuvant, it enhances the production of antigen-specific antibodies in vaccine models. The conjugate does not affect protein folding or disrupt key epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.
|
-
- HY-20755
-
TFA-NH-(CH2)2-OH
|
Biochemical Assay Reagents
|
2,2-Trifluoro-N-(2-hydroxyethyl) acetamide (TFA-NH-(CH2)2-OH) is a carboxylic acid that can be used as a molecular block.
|
-
- HY-161491
-
|
Biochemical Assay Reagents
|
1-(2-Aminoethyl)-1H-pyrazol-4-ylphosphonic acid-linker/OVA is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-W002570
-
|
Biochemical Assay Reagents
|
Naphthalen-2-boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40174A
-
|
Biochemical Assay Reagents
|
tert-Butyl (2-aminoethyl)(methyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-161527
-
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-W012883
-
-
- HY-P4154
-
ALM-488
|
Fluorescent Dye
|
Neurological Disease
Cancer
|
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .
|
-
- HY-P3815
-
|
Casein Kinase
|
Others
|
Casein Kinase 2 Substrate Peptide is a common CK2 substrate peptide. Casein Kinase 2 Substrate Peptide is synthesized with its C-terminus conjugated to 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid (EDANS). Casein Kinase 2 Substrate Peptide can be used for protein kinase CK2 activity determination .
|
-
- HY-W039763
-
-
- HY-W009197
-
-
- HY-W008489
-
-
- HY-W011322
-
-
- HY-W053701
-
|
Amino Acid Derivatives
|
Others
|
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((5-(dimethylamino)naphthalen-1-yl)sulfonyl)-L-lysine is a lysine derivative .
|
-
- HY-P4757
-
|
Peptides
|
Others
|
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
|
-
- HY-P1103A
-
|
CXCR
|
Cancer
|
CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
|
-
- HY-P1103
-
|
CXCR
|
Cancer
|
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
|
-
- HY-P4756
-
|
Peptides
|
Others
|
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P2231A
-
MEDI0382 acetate
|
GCGR
|
Metabolic Disease
|
Cotadutide (MEDI0382) acetate is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide acetate exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide acetate can be used in the research of obesity and type 2 diabetes (T2D) .
|
-
- HY-P2075
-
|
Renin
|
Endocrinology
|
EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .
|
-
- HY-P0009A
-
-
- HY-P0009B
-
-
- HY-P2231
-
MEDI0382
|
GCGR
|
Metabolic Disease
|
Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D) .
|
-
- HY-P10026
-
LY-3457263
|
Peptides
|
Metabolic Disease
|
Nisotirotide (LY-3457263) is a PYY analog agonist studied in type 2 diabetes and obesity .
|
-
- HY-P10472
-
|
GnRH Receptor
|
Endocrinology
|
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
|
-
- HY-P10341
-
|
GCGR
|
Metabolic Disease
|
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .
|
-
- HY-131374
-
|
CXCR
|
Cancer
|
TN14003 is a CXCR4 inhibitor. TN14003 has antitumor activity .
|
-
- HY-P1321
-
1229U91; GW1229
|
Neuropeptide Y Receptor
|
Neurological Disease
|
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
|
-
- HY-P1321A
-
1229U91 TFA; GW1229 TFA
|
Neuropeptide Y Receptor
|
Neurological Disease
|
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
|
-
- HY-P3066
-
d(CH2)5Tyr(Et)VAVP
|
Vasopressin Receptor
|
Metabolic Disease
|
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
|
-
- HY-P4146
-
BI 456906
|
GLP Receptor
GCGR
|
Metabolic Disease
|
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
|
-
- HY-P4146A
-
BI 456906 TFA
|
GLP Receptor
GCGR
|
Metabolic Disease
|
Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-Y0946S
-
|
Acetamide- 15N is the 15N-labeled Acetamide. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity[1][2].
|
-
Cat. No. |
Product Name |
|
Classification |
-
- HY-136205
-
Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide
|
|
Alkynes
|
IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection . IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling . IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
Cat. No. |
Product Name |
|
Classification |
-
- HY-152727
-
|
|
Nucleosides and their Analogs
|
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(naphthalen-1-yl)purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
|
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