2. PROTAC
  3. PROTAC Linkers
  4. N-Me-N-bis(PEG4-acid)

N-Me-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

N-Me-N-bis(PEG4-acid) Chemical Structure

N-Me-N-bis(PEG4-acid) Chemical Structure

CAS No. : 2055014-77-0

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N-Me-N-bis(PEG4-acid) Related Antibodies

Top Publications Citing Use of Products

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

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Description

N-Me-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

N-Me-N-bis(PEG4-acid) Related Antibodies
Molecular Weight

527.60

Formula

C23H45NO12
CAS No.
Appearance

Viscous Liquid

Color

Colorless to off-white

SMILES

O=C(O)CCOCCOCCOCCOCCN(C)CCOCCOCCOCCOCCC(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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N-Me-N-bis(PEG4-acid) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Me-N-bis(PEG4-acid)2055014-77-0PROTAC LinkersInhibitorinhibitorinhibit

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