1. Metabolic Enzyme/Protease
  2. NAMPT
  3. NAMPT degrader-3

NAMPT degrader-3 (compound C5) is a NAMPT degrader, depending on VHL- and proteasome manner. NAMPT degrader-3 displays cytotoxicity and inhibits A2780 cells proliferation.

For research use only. We do not sell to patients.

NAMPT degrader-3 Chemical Structure

NAMPT degrader-3 Chemical Structure

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Description

NAMPT degrader-3 (compound C5) is a NAMPT degrader, depending on VHL- and proteasome manner. NAMPT degrader-3 displays cytotoxicity and inhibits A2780 cells proliferation[1].

Molecular Weight

1003.30

Formula

C56H74N8O7S

SMILES

O=C([C@@H](NC(CCCCCCCNC(C1=CC=C(C(N2CCC(CC2)CCCCNC(/C=C/C3=CC=CN=C3)=O)=O)C=C1)=O)=O)C(C)(C)C)N4C[C@@H](C[C@H]4C(N[C@H](C5=CC=C(C6=C(C)N=CS6)C=C5)C)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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NAMPT degrader-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
NAMPT degrader-3
Cat. No.:
HY-155506
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