Nepasaikosaponin K

Cat. No.: HY-N7915: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Nepasaikosaponin K is an anti-influenza agent. Nepasaikosaponin K shows an EC₅₀ of 17.91 μM against influenza virus A/WSN/33 (H1N1) in 239T-Gluc cells.

For research use only. We do not sell to patients.

Nepasaikosaponin K Chemical Structure

CAS No. : 405229-61-0

Size	Stock	Quantity
1 mg	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
5 mg	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

Synthetic products have potential research and development risk.

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Nepasaikosaponin K is an anti-influenza agent. Nepasaikosaponin K shows an EC₅₀ of 17.91 μM against influenza virus A/WSN/33 (H1N1) in 239T-Gluc cells^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HEK-293T	CC₅₀	> 200 μM Compound: 12	Cytotoxicity against human 293T cells expressing Gluc assessed as inhibition of cell proliferation after 24 hrs by CCK8 assay Cytotoxicity against human 293T cells expressing Gluc assessed as inhibition of cell proliferation after 24 hrs by CCK8 assay	[PMID: 28314599]

Molecular Weight

945.14

Formula

C₄₈H₈₀O₁₈

CAS No.

405229-61-0

SMILES

C[C@]([C@@]1([H])[C@]2(CC[C@@H]3O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O[C@H](O[C@H]5C)[C@@H]([C@@H]([C@H]5O)O)O)CO[C@@H]([C@@H]([C@H]6O)O)O[C@@H]([C@H]6O)CO)C)(CC[C@@]2([H])[C@]3(C)CO)[C@@](C([C@@](CC7(C)C)([H])[C@@]8(CC7)CO)=CC1)(C[C@@H]8O)C

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Fang W, et al. Anti-influenza triterpenoid saponins (saikosaponins) from the roots of Bupleurum marginatum var. stenophyllum. Bioorg Med Chem Lett. 2017 Apr 15;27(8):1654-1659. [Content Brief]