1. Metabolic Enzyme/Protease
  2. Phosphatase
  3. NFh-ALP

NFh-ALP is an alkaline phosphatase (ALP)-activatable photosensitizer. NFh-ALP could be activated by ALP in cells and generate 1O2 under 808 nm excitation, effectively killing tumor cells by inducing apoptosis and having good biocompatibility. The maximum absorption wavelength of NFh-ALP is about 656 nm.

For research use only. We do not sell to patients.

NFh-ALP Chemical Structure

NFh-ALP Chemical Structure

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Description

NFh-ALP is an alkaline phosphatase (ALP)-activatable photosensitizer. NFh-ALP could be activated by ALP in cells and generate 1O2 under 808 nm excitation, effectively killing tumor cells by inducing apoptosis and having good biocompatibility. The maximum absorption wavelength of NFh-ALP is about 656 nm[1].

Molecular Weight

763.19

Formula

C27H27Br2INO5P

SMILES

CC1(C)C(/C=C/C(CCC2)=C3C2=CC(C=C(Br)C(OP(O)(O)=O)=C4)=C4O3)=[N+](CC)C5=CC=C(Br)C=C15.[I-]

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
NFh-ALP
Cat. No.:
HY-159485
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