NIOCH 14

Cat. No.: HY-147016: FAQs
Data Sheet Handling Instructions

Molarity Calculator

NIOCH 14 is a antiviral agent and a pro-agent. NIOCH 14 has antiviral activity against orthopoxviruses. NIOCH 14 can significantly lower proportions of infected mice, and virus production levels in the lungs. NIOCH 14 can be used for researching anti-smallpox. NIOCH 14 shows anti-orthopoxvirus activity.

For research use only. We do not sell to patients.

NIOCH 14 Chemical Structure

CAS No. : 1268015-38-8

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Orthopoxviruses^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
Vero	CC₅₀	1193.4 μM Compound: NIOCH-14	Cytotoxicity against African green monkey Vero cells measured after 4 days by colorimetric assay Cytotoxicity against African green monkey Vero cells measured after 4 days by colorimetric assay	[PMID: 36414175]

Molecular Weight

394.34

Formula

C₁₉H₁₇F₃N₂O₄

CAS No.

1268015-38-8

SMILES

O=C(C1C2C=CC(C3CC23)C1C(NNC(C4=CC=C(C(F)(F)F)C=C4)=O)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sokolova AS, et al. (+)-Camphor and (-)-borneol derivatives as potential anti-orthopoxvirus agents. Arch Pharm (Weinheim). 2021;354(6):e2100038. [Content Brief]

[2]. Mazurkov OY, et al. New effective chemically synthesized anti-smallpox compound NIOCH-14. J Gen Virol. 2016;97(5):1229-1239. [Content Brief]

[3]. Anastasiya S Sokolova, et al. (+)-Camphor and (-)-borneol derivatives as potential anti-orthopoxvirus agents. Arch Pharm (Weinheim). 2021 Jun;354(6):e2100038. [Content Brief]

NIOCH 14 Related Classifications

Infection

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NIOCH 141268015-38-8NIOCH14NIOCH-14OrthopoxvirusOrthopoxvirusesAnti-smallpoxInhibitorinhibitorinhibit

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