1. Protein Tyrosine Kinase/RTK Autophagy
  2. IGF-1R Insulin Receptor Autophagy
  3. NVP-AEW541 dihydrochloride

NVP-AEW541 dihydrochloride  (Synonyms: AEW541 dihydrochloride)

Cat. No.: HY-50866B
Handling Instructions

NVP-AEW541 dihydrochloride (AEW541 dihydrochloride) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC50 value of 0.15 μM. NVP-AEW541 dihydrochloride also inhibits InsR, IC50 with a value of 0.14 μM. NVP-AEW541 dihydrochloride has antitumor activity.

For research use only. We do not sell to patients.

NVP-AEW541 dihydrochloride Chemical Structure

NVP-AEW541 dihydrochloride Chemical Structure

CAS No. : 2320261-63-8

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Description

NVP-AEW541 dihydrochloride (AEW541 dihydrochloride) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC50 value of 0.15 μM. NVP-AEW541 dihydrochloride also inhibits InsR, IC50 with a value of 0.14 μM. NVP-AEW541 dihydrochloride has antitumor activity[1].

Molecular Weight

512.47

Formula

C27H31Cl2N5O

CAS No.
SMILES

[H]Cl.[H]Cl.NC1=C2C(N([C@@H]3C[C@@H](C3)CN4CCC4)C=C2C5=CC=CC(OCC6=CC=CC=C6)=C5)=NC=N1

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NVP-AEW541 dihydrochloride
Cat. No.:
HY-50866B
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