2. Metabolic Enzyme/Protease
  3. Factor Xa
  4. O-Desmethyl apixaban sulfate sodium

O-Desmethyl apixaban sulfate sodium is a major circulating metabolite of Apixaban in humans. O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM.

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O-Desmethyl apixaban sulfate sodium Chemical Structure

O-Desmethyl apixaban sulfate sodium Chemical Structure

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Based on 1 publication(s) in Google Scholar

O-Desmethyl apixaban sulfate sodium Related Antibodies

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Description

O-Desmethyl apixaban sulfate sodium is a major circulating metabolite of Apixaban in humans. O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM[1][2].

IC50 & Target

Ki: 58 μM (Factor Xa)[1]
Molecular Weight

547.52

Formula

C24H22N5NaO7S
SMILES

O=C(C1=NN(C2=CC=C(OS(=O)(O[Na])=O)C=C2)C3=C1CCN(C4=CC=C(N5C(CCCC5)=O)C=C4)C3=O)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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O-Desmethyl apixaban sulfate sodium Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

O-Desmethyl apixaban sulfateFactor XaFxaCirculatingmetaboliteFXaInhibitorinhibitorinhibit

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