1. Metabolic Enzyme/Protease
  2. Carbonic Anhydrase Drug Metabolite
  3. O-Desmethyl Brinzolamide hydrochloride

O-Desmethyl Brinzolamide hydrochloride (compound 6a), an active metabolite of Brinzolamide, is a carbonic anhydrase (CA) inhibitor with a Kd of 0.136 nM for CA II and an IC50 of 165 nM for CA IV.

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O-Desmethyl Brinzolamide hydrochloride Chemical Structure

O-Desmethyl Brinzolamide hydrochloride Chemical Structure

CAS No. : 2967475-56-3

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Description

O-Desmethyl Brinzolamide hydrochloride (compound 6a), an active metabolite of Brinzolamide, is a carbonic anhydrase (CA) inhibitor with a Kd of 0.136 nM for CA II and an IC50 of 165 nM for CA IV[1].

Molecular Weight

405.94

Formula

C11H20ClN3O5S3

CAS No.
SMILES

CCN[C@H]1CN(CCCO)S(=O)(C2=C1C=C(S(=O)(N)=O)S2)=O.[H]Cl

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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O-Desmethyl Brinzolamide hydrochloride Related Classifications

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Product Name:
O-Desmethyl Brinzolamide hydrochloride
Cat. No.:
HY-W424792A
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