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  4. o,p'-DDE

o,p'-DDE  (Synonyms: 2,4'-DDE; 2,4-Dichlorodiphenyldichloroethylene; 2,4'-DDE; o,p'-Dichlorodiphenyldichloroethylene)

Cat. No.: HY-121779
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o,p'-DDE (2,4-Dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT. It accumulates in smallmouth buffalo, channel catfish, and largemouth bass, and in sediments from DDT manufacturing plants around the Huntsville Spring Branch-Indian Creek tributary system, where it is considered a persistent organic pollutant (POP). o,p'-DDE inhibits estrogen binding to the rainbow trout estrogen receptor (rtER) with an IC50 value of 3.2 μM. It induces concentration-dependent estradiol secretion in co-cultures of granulosa and theca cells isolated from porcine follicles. In ovo exposure to o,p'-DDE increases follicular degeneration and reduces testis size in Japanese medaka (O. latipes).

For research use only. We do not sell to patients.

o,p'-DDE Chemical Structure

o,p'-DDE Chemical Structure

CAS No. : 3424-82-6

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o,p'-DDE Related Antibodies

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Description

o,p'-DDE (2,4-Dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT. It accumulates in smallmouth buffalo, channel catfish, and largemouth bass, and in sediments from DDT manufacturing plants around the Huntsville Spring Branch-Indian Creek tributary system, where it is considered a persistent organic pollutant (POP). o,p'-DDE inhibits estrogen binding to the rainbow trout estrogen receptor (rtER) with an IC50 value of 3.2 μM. It induces concentration-dependent estradiol secretion in co-cultures of granulosa and theca cells isolated from porcine follicles. In ovo exposure to o,p'-DDE increases follicular degeneration and reduces testis size in Japanese medaka (O. latipes).

Molecular Weight

318.03

Formula

C14H8Cl4
CAS No.
SMILES

ClC1=CC=C(C=C1)/C(C2=CC=CC=C2Cl)=C(Cl)/Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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o,p'-DDE Related Classifications

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Keywords:

o,p'-DDE3424-82-62,4'-DDE 2,4-Dichlorodiphenyldichloroethylene 2,4'-DDE o,p'-DichlorodiphenyldichloroethyleneOthersInhibitorinhibitorinhibit

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