1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. ODN INH 18

ODN INH-18 is a linear 24-mer class B INH-ODN in which the 5' INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 showes inhibitory potency for TLR9 ligand-induced IFN-α production.

The free form of the compound is prone to instability, it is advisable to consider the stable salt form (ODN INH 18 sodium) that retains the same biological activity.

For research use only. We do not sell to patients.

DNA, d(P-thio)(C-C-T-G-G-A-T-G-G-G-A-A-C-T-T-A-C-C-G-C-T-G-C-A)

ODN INH 18 Chemical Structure

CAS No. : 1934318-43-0

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Description

ODN INH-18 is a linear 24-mer class B INH-ODN in which the 5' INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 showes inhibitory potency for TLR9 ligand-induced IFN-α production.

Molecular Weight

7723.29

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[ODN INH 18]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
ODN INH 18
Cat. No.:
HY-153840
Quantity:
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