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  4. ONC1-13B

ONC1-13B is a potent androgen receptor (AR) antagonist with the activity of effectively inhibiting PSA expression in prostate cancer cells. ONC1-13B can effectively inhibit PSA expression and prostate cancer cell proliferation under DHT stimulation. ONC1-13B exerts its anti-tumor effect by preventing androgen from binding to AR and its nuclear translocation.

For research use only. We do not sell to patients.

ONC1-13B Chemical Structure

ONC1-13B Chemical Structure

CAS No. : 1351185-54-0

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ONC1-13B Related Antibodies

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Description

ONC1-13B is a potent androgen receptor (AR) antagonist with the activity of effectively inhibiting PSA expression in prostate cancer cells. ONC1-13B can effectively inhibit PSA expression and prostate cancer cell proliferation under DHT stimulation. ONC1-13B exerts its anti-tumor effect by preventing androgen from binding to AR and its nuclear translocation[1].

Molecular Weight

492.45

Formula

C22H16F4N4O3S
CAS No.
SMILES

O=C1[C@]2(CCOC2)N(C3=CC(F)=C(C=C3)C(NC)=O)C(N1C4=CC(C(F)(F)F)=C(C=C4)C#N)=S
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ONC1-13B Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ONC1-13B1351185-54-0OthersInhibitorinhibitorinhibit

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HY-114246
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