Oxytocin parallel dimer TFA 

Oxytocin parallel dimer TFA is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin^[1][2].

The parallel and antiparallel homo/hetero bis-cystine dimers of oxytocin and deamino-oxytocin show biological activities ranged from 0.2% to 6% that of oxytocin^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Oxytocin dimer (iv; single dose) shows acute toxicity (LD₅₀=43 mg/kg) is less than that of oxytocin (LD₅₀=25 mg/kg) in rats^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2128.40

C₈₈H₁₃₃F₃N₂₄O₂₆S₄

Solid

White to off-white

Sequence 1:CYIQNCPLG-NH2;Sequence 2:CYIQNCPLG-NH2 (Disulfide bridge:Chain1 Cys1 to Chain2 Cys1;Chain1 Cys6 to Chain2 Cys6)

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light, under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

• [1]. Chen L, et al. Syntheses and biological activities of parallel and antiparallel homo and hetero bis-cystine dimers of oxytocin and deamino-oxytocin. Pept Res. 1996;9(3):114-121.  [Content Brief]

  [2]. Berde B, et al. Some pharmacological properties of oxytocin-dimers (α+ β)[J]. Experientia, 1971, 27: 1304-1305.