1. Membrane Transporter/Ion Channel
  2. P-glycoprotein
  3. P-gp modulator 1

P-gp modulator 1 is a high affinity, orally available modulator of P-glycoprotein (Pgp), can reverse the Pgp-mediated multidrug resistance ((MDR).

For research use only. We do not sell to patients.

P-gp modulator 1 Chemical Structure

P-gp modulator 1 Chemical Structure

CAS No. : 2249749-39-9

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Description

P-gp modulator 1 is a high affinity, orally available modulator of P-glycoprotein (Pgp), can reverse the Pgp-mediated multidrug resistance ((MDR)[1].

IC50 & Target

P-glycoprotein

Molecular Weight

689.02

Formula

C41H72N2O6

CAS No.
SMILES

CC(C)(O)[C@H](O1)CC[C@@]1(C)[C@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5([H])C(C)(C)[C@@H](NC(CCCCCNC(OC(C)(C)C)=O)=O)CC[C@]5(C)[C@@]4([H])C[C@@H](O)[C@@]32[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
P-gp modulator 1
Cat. No.:
HY-112912
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