2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. PAT-IN-2

PAT-IN-2 is a protein acyl transferases (PAT) inhibitor. PAT-IN-2 competitively inhibits Erf2 autopalmitoylation (WO2017011518A1; compound 25).

For research use only. We do not sell to patients.

PAT-IN-2 Chemical Structure

PAT-IN-2 Chemical Structure

CAS No. : 2066572-01-6

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PAT-IN-2 Related Antibodies

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Description

PAT-IN-2 is a protein acyl transferases (PAT) inhibitor. PAT-IN-2 competitively inhibits Erf2 autopalmitoylation (WO2017011518A1; compound 25)[1].

In Vitro

PAT-IN-2 (compound 25) completely inhibits growth of RJY1941 (control) at 20 μΜ, but has no detectable effect at lower concentrations. PAT-IN-2 inhibits the growth of RJY1942 (palmitoylation sensitive) at 5 μΜ[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PAT-IN-2 Related Antibodies
Molecular Weight

746.91

Formula

C42H56F6N4O
CAS No.
SMILES

CC(C1=CC=C(C=C1)CC(C)C)CN(CCN(C2)CCCC[C@@H]3N(CCNC3)CCC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)[C@H]2CC5=CC=C(C=C5)O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PAT-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PAT-IN-22066572-01-6Raspalmitoylationprotein acyl transferaseErf2 autopalmitoylationInhibitorinhibitorinhibit

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