2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. Patiromer

Patiromer is an orally active and potent hyperkalemia inhibitor and a nonabsorbed potassium binder. Patiromer polymer is bound with calcium which is released in the colon in exchange for binding potassium.

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Patiromer Chemical Structure

Patiromer Chemical Structure

CAS No. : 1208912-84-8

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Description

Patiromer is an orally active and potent hyperkalemia inhibitor and a nonabsorbed potassium binder. Patiromer polymer is bound with calcium which is released in the colon in exchange for binding potassium[1][2].

Clinical Trial
Formula

C28H48CaFO2+
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CCC(C([O-])=O)(F)CC(C1=CC=CC=C1)CC(CCCCC(C)CC)C.CC(CC)C.[Ca+2].[p].[p].[n].[m].[n].[1/2]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at 4°C, do not freeze
Solvent & Solubility
In Vitro: 

H2O : < 0.1 mg/mL (insoluble)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥95.0%

COA (231 KB)

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Patiromer Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Patiromer1208912-84-8Potassium ChannelKcsAelectrolyte disorderdialysisheart failurehyperkalemiahypertensionpatiromerpotassiumkidney diseaseInhibitorinhibitorinhibit

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