2. Autophagy PROTAC Metabolic Enzyme/Protease
  3. ATTECs PCSK9
  4. PCSK9 autophagic degrader 2

PCSK9 autophagic degrader 2 (W6) is a PCSK9 targeted autophagosome, with an DC50 of 20.6 nM. PCSK9 autophagic degrader 2 (W6) demonstrates comparable antiatherosclerosis effect and exhibits a KD of 2.5 μM for LC3B (Pink: PCSK9 ligand HY-176044; Blue: LC3B ligand HY-176045; Black: linker HY-141373).

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PCSK9 autophagic degrader 2 Chemical Structure

PCSK9 autophagic degrader 2 Chemical Structure

CAS No. : 2974497-11-3

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PCSK9 autophagic degrader 2 Related Antibodies

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Description

PCSK9 autophagic degrader 2 (W6) is a PCSK9 targeted autophagosome, with an DC50 of 20.6 nM. PCSK9 autophagic degrader 2 (W6) demonstrates comparable antiatherosclerosis effect and exhibits a KD of 2.5 μM for LC3B (Pink: PCSK9 ligand HY-176044; Blue: LC3B ligand HY-176045; Black: linker HY-141373)[1].

In Vitro

PCSK9 autophagic degrader 2 (W6) degrades PCSK9 via autophagy by linking PCSK9 and LC3B together[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PCSK9 autophagic degrader 2 Related Antibodies
Molecular Weight

1012.54

Formula

C39H41Br2IN4O8S
CAS No.
SMILES

O=C(NC1=NC=CS1)CC2(C)NCCC3=C2C=C(OCCOCCOCCOCCN4C(/C(C5=C4C=CC(I)=C5)=C/C6=CC(Br)=C(O)C(Br)=C6)=O)C(OC)=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PCSK9 autophagic degrader 2 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PCSK9 autophagic degrader 22974497-11-3ATTECsPCSK9Autophagosome-tethering compoundsProprotein convertase subtilisin/kexin type 9autophagosome,Inhibitorinhibitorinhibit

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