2. MAPK/ERK Pathway Autophagy Anti-infection
  3. p38 MAPK Autophagy Enterovirus
  4. PD 169316 (Standard)

PD 169316 (Standard) is the analytical standard of PD 169316 (HY-10578). This product is intended for research and analytical applications. PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor, with IC50 of 89 nM. PD169316 selectively inhibits the kinase activity of the phosphorylated p38 without hindering upstream kinases to phosphorylate p38. PD169316 shows antiviral activity against Enterovirus71. PD169316 shows antiviral activity against Enterovirus71.

For research use only. We do not sell to patients.

PD 169316 (Standard) Chemical Structure

PD 169316 (Standard) Chemical Structure

CAS No. : 152121-53-4

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Description

PD 169316 (Standard) is the analytical standard of PD 169316 (HY-10578). This product is intended for research and analytical applications. PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor, with IC50 of 89 nM. PD169316 selectively inhibits the kinase activity of the phosphorylated p38 without hindering upstream kinases to phosphorylate p38. PD169316 shows antiviral activity against Enterovirus71. PD169316 shows antiviral activity against Enterovirus71.

Molecular Weight

360.34

Formula

C20H13FN4O2
CAS No.
SMILES

FC1=CC=C(C2=C(NC(C3=CC=C(C=C3)[N+]([O-])=O)=N2)C4=CC=NC=C4)C=C1
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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PD 169316 (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PD 169316 (Standard)152121-53-4p38 MAPKAutophagyEnterovirusRhinovirusHRVHRVsHEVHEVsInhibitorinhibitorinhibit

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