2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. PDE10A-IN-5

PDE10A-IN-5 (Compound A30) is an inhibitor of phosphodiesterase 10A (PDE10A) with oral activity, and its IC50 value is 3.5 nM. PDE10A-IN-5 exerts the activity of inhibiting pulmonary vascular remodeling by inhibiting PDE10A and activating the cyclic adenosine monophosphate (cAMP)-associated signaling pathway, and can be used for research in the field of pulmonary arterial hypertension.

For research use only. We do not sell to patients.

PDE10A-IN-5 Chemical Structure

PDE10A-IN-5 Chemical Structure

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PDE10A-IN-5 Related Antibodies

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Description

PDE10A-IN-5 (Compound A30) is an inhibitor of phosphodiesterase 10A (PDE10A) with oral activity, and its IC50 value is 3.5 nM. PDE10A-IN-5 exerts the activity of inhibiting pulmonary vascular remodeling by inhibiting PDE10A and activating the cyclic adenosine monophosphate (cAMP)-associated signaling pathway, and can be used for research in the field of pulmonary arterial hypertension[1].

IC50 & Target

PDE10A

3.5 nM (IC50)

Molecular Weight

514.62

Formula

C29H34N6O3
SMILES

O=C(C1=C(C2CN(C3=NC4=CC=CC=C4C(C(NCCN(CC)CC)=O)=C3)C2)N=C5C=CC=CN51)OCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PDE10A-IN-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PDE10A-IN-5Phosphodiesterase (PDE)Inhibitorinhibitorinhibit

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