PEG2000  (Synonyms: Polyethylene glycol 2000)

PEG2000 (Polyethylene glycol 2000) is a solvent for a large number of substances. PEG2000 can be used as a carrier material and modifying agent. PEG2000 is widely used in a variety of pharmaceutical formulations^[1].

The FDA has approved polyethylene glycol (PEG) for use as a vehicle or base in foods, cosmetics and pharmaceuticals, including injectable, topical, rectal and nasal formulations. PEG shows little toxicity, and is eliminated from the body intact by either the kidneys (for PEGs < 30 kDa) or in the faeces (for PEGs > 20 kDa). PEG lacks immunogenicity, and antibodies to PEG are generated in rabbits only if PEG is combined with highly immunogenic proteins^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2000.00

25322-68-3

Solid

White to off-white

[H]OCCO[H].[n]

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Hong Y, et al. Effect of PEG2000 on drug delivery characterization from solid lipid nanoparticles. Pharmazie. 2006 Apr;61(4):312-5.  [Content Brief]

  [2]. Harris JM, et al. Effect of pegylation on pharmaceuticals. Nat Rev Drug Discov. 2003 Mar;2(3):214-21.  [Content Brief]