2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. PF-07038124

PF-07038124 is a PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2. PF-07038124 shows inhibitory activities against IL-13, IL4, and IFNγ (IC50=125, 4.1, 1.06 nM, respectively). PF-07038124 can be used for research of atopic dermatitis and plaque psoriasis.

For research use only. We do not sell to patients.

PF-07038124 Chemical Structure

PF-07038124 Chemical Structure

CAS No. : 2415085-44-6

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PF-07038124 Related Antibodies

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Description

PF-07038124 is a PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2. PF-07038124 shows inhibitory activities against IL-13, IL4, and IFNγ (IC50=125, 4.1, 1.06 nM, respectively). PF-07038124 can be used for research of atopic dermatitis and plaque psoriasis[1][2].

IC50 & Target[1]

PDE4B2

0.5 nM (IC50)

Molecular Weight

327.18

Formula

C18H22BNO4
CAS No.
SMILES

CCCOC1=C(OC)C=CC(C2=CN=CC([C@@]3([H])CB(OC3)O)=C2)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PF-07038124 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PF-070381242415085-44-6PF07038124PF 07038124Phosphodiesterase (PDE)atopic dermatitisplaque psoriasisInhibitorinhibitorinhibit

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