2. PROTAC
  3. PROTAC Linkers
  4. Pip-alkyne-Ph-COOCH3

Pip-alkyne-Ph-COOCH3 is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTAC ARD-266. Pip-alkyne-Ph-COOCH3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Pip-alkyne-Ph-COOCH3 Chemical Structure

Pip-alkyne-Ph-COOCH3 Chemical Structure

CAS No. : 2308496-47-9

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Pip-alkyne-Ph-COOCH3 Related Antibodies

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Description

Pip-alkyne-Ph-COOCH3 is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTAC ARD-266[1]. Pip-alkyne-Ph-COOCH3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target[1]

Alkyl-Chain

 

In Vitro

ARD-266 is a a highly potent and VHL E3 ligase-based androgen receptor (AR) PROTAC degrader[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Pip-alkyne-Ph-COOCH3 Related Antibodies
Molecular Weight

243.30

Formula

C15H17NO2
CAS No.
SMILES

O=C(OC)C1=CC=C(C#CC2CCNCC2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Pip-alkyne-Ph-COOCH3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pip-alkyne-Ph-COOCH32308496-47-9PROTAC LinkersInhibitorinhibitorinhibit

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