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Piperafizine A (compound 4d’) is a N-monoalkylated plinabulin derivative. Anti-cancer reagent.

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Piperafizine A Chemical Structure

Piperafizine A Chemical Structure

CAS No. : 130603-59-7

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Based on 1 publication(s) in Google Scholar

Piperafizine A Related Antibodies

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Description

Piperafizine A (compound 4d’) is a N-monoalkylated plinabulin derivative. Anti-cancer reagent[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
7.8 μM
Compound: Piperafizine A
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
[PMID: 27318124]
DU-145 IC50
9.4 μM
Compound: Piperafizine A
Cytotoxicity against human DU-145 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against human DU-145 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
[PMID: 27318124]
HeLa IC50
4.9 μM
Compound: Piperafizine A
Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
[PMID: 27318124]
HT-29 IC50
6.5 μM
Compound: Piperafizine A
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
[PMID: 27318124]
K562 IC50
2.9 μM
Compound: Piperafizine A
Cytotoxicity against human K562 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against human K562 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
[PMID: 27318124]
MCF7 IC50
5.1 μM
Compound: Piperafizine A
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
[PMID: 27318124]
U-937 IC50
1.4 μM
Compound: Piperafizine A
Cytotoxicity against human U-937 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Cytotoxicity against human U-937 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
[PMID: 27318124]
Molecular Weight

304.34

Formula

C19H16N2O2
CAS No.
SMILES

O=C(N(/C1=C\C2=CC=CC=C2)C)/C(NC1=O)=C/C3=CC=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Piperafizine A Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Piperafizine A130603-59-7OtherspiperafizineN-monoalkylated plinabulinanti-cancerInhibitorinhibitorinhibit

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