PKCθ pseudosubstrate peptide inhibitor,myristoylated TFA 

PKCθ pseudosubstrate peptide inhibitor, myristoylated TFA is a synthetic peptide that can be used to study the mechanism of action of PKCθ^[1].

2318.88 (free base)

C₁₀₅H₁₈₄N₃₆O₂₁S.xC₂HF₃O₂

Solid

White to off-white

{Myr}-Leu-His-Gln-Arg-Arg-Gly-Ala-Ile-Lys-Gln-Ala-Lys-Val-His-His-Val-Lys-Cys-NH2

{Myr}-LHQRRGAIKQAKVHHVKC-NH2

O=C([C@@H](NC(CCCCCCCCCCCCC)=O)CC(C)C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CS)=O)CCCCN)=O)C(C)C)=O)CC1=CNC=N1)=O)CC2=CNC=N2)=O)C(C)C)=O)CCCCN)=O)C)=O)CCC(N)=O)=O)CCCCN)=O)[C@H](CC)C)=O)C)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CC3=CNC=N3.OC(C(F)(F)F)=O.[x]

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Koon HW, et al. Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves protein kinase Cdelta activation. J Pharmacol Exp Ther. 2005 Sep;314(3):1393-400.  [Content Brief]