2. Metabolic Enzyme/Protease
  3. Pyruvate Kinase
  4. PKM2 activator 3

PKM2 activator 3 is a potent PKM2 activator with an AC50 value of 90 nM. PKM2 activator 3 has good Caco-2 permeability, a low efflux ratio and high microsomal stability. PKM2 activator 3 can be used for researching anticancer.
(AC50: the concentration which gives 50% activation of enzyme.)

For research use only. We do not sell to patients.

PKM2 activator 3 Chemical Structure

PKM2 activator 3 Chemical Structure

CAS No. : 1346113-84-5

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PKM2 activator 3 Related Antibodies

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Description

PKM2 activator 3 is a potent PKM2 activator with an AC50 value of 90 nM. PKM2 activator 3 has good Caco-2 permeability, a low efflux ratio and high microsomal stability. PKM2 activator 3 can be used for researching anticancer[1].
(AC50: the concentration which gives 50% activation of enzyme.)

IC50 & Target

PKM2[1]
In Vivo

PKM2 activator 3 (compound 66) has good Caco-2 permeability, a low efflux ratio (0.84) and high microsomal stability (t1/2 = 277.2 min in human liver microsomes and 117.5 min in mouse liver microsomes)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

372.77

Formula

C15H11ClF2N2O3S
CAS No.
SMILES

FC1=C(Cl)C=C(NS(=O)(C(C=C2CC3)=C(F)C=C2NC3=O)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PKM2 activator 3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PKM2 activator 31346113-84-5Pyruvate KinasePKM2anticancerInhibitorinhibitorinhibit

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