1. Anti-infection
  2. SARS-CoV
  3. PLP_Snyder530

PLP_Snyder530 is a potent papain-like protease (PLpro) inhibitor with an IC50 value of 6.4 μM. PLP_Snyder530 induces conformational changes in SARS-COV-2 papain-like protease, inhibiting SARS-CoV-2 replication. PLP_Snyder530 can be used for SARS-CoV-2 research.

For research use only. We do not sell to patients.

PLP_Snyder530 Chemical Structure

PLP_Snyder530 Chemical Structure

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Description

PLP_Snyder530 is a potent papain-like protease (PLpro) inhibitor with an IC50 value of 6.4 μM. PLP_Snyder530 induces conformational changes in SARS-COV-2 papain-like protease, inhibiting SARS-CoV-2 replication. PLP_Snyder530 can be used for SARS-CoV-2 research[1].

IC50 & Target

IC50: 6.4 μM (papain-like protease)[1]

In Vitro

PLP_Snyder530 induces conformational changes manly in BL2 region and increases the activity against PLpro[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

372.46

Formula

C24H24N2O2

SMILES

C=CC(NC1=CC=C(C(C(C([C@@H](C2=CC=CC3=CC=CC=C32)C)N)=O)=C1)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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PLP_Snyder530 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PLP_Snyder530
Cat. No.:
HY-150786
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