1. Anti-infection
  2. Bacterial
  3. Polyalanine peptide

Polyalanine peptide (pALA) is an antimicrobial peptide that targets biofilms and Gram-negative bacteria and is non-toxic to mammalian cells. Polyalanine peptide forms an α-helical conformation that effectively permeabilizes Gram-negative bacterial membranes, thereby inducing lethal cell leakage. Polyalanine peptide can be used in anti-infection research.

For research use only. We do not sell to patients.

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Polyalanine peptide Chemical Structure

Polyalanine peptide Chemical Structure

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Description

Polyalanine peptide (pALA) is an antimicrobial peptide that targets biofilms and Gram-negative bacteria and is non-toxic to mammalian cells. Polyalanine peptide forms an α-helical conformation that effectively permeabilizes Gram-negative bacterial membranes, thereby inducing lethal cell leakage. Polyalanine peptide can be used in anti-infection research[1].

Molecular Weight

743.81

Formula

C31H53N9O12

Sequence

Ala-Ala-Ala-Asp-Ala-Ala-Ala-Ala-Leu

Sequence Shortening

AAADAAAAL

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Polyalanine peptide
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HY-P10546
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