1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. Polθ-IN-6

Polθ-IN-6 (Compound 89) is a DNA polymerase theta (Polθ) inhibitor. Polθ-IN-6 has antitumor activity.

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Polθ-IN-6 Chemical Structure

Polθ-IN-6 Chemical Structure

CAS No. : 3058496-94-6

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Description

Polθ-IN-6 (Compound 89) is a DNA polymerase theta (Polθ) inhibitor. Polθ-IN-6 has antitumor activity[1].

Molecular Weight

445.53

Formula

C25H23N3O3S

CAS No.
SMILES

O=C(C1=CN=C(C)C=C1C2=C(OC)C=CC=C2)NC3=NC4=C(S3)C=C(C5OCCC5)C=C4

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Polθ-IN-6
Cat. No.:
HY-169285
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