2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Pomalidomide 4'-PEG5-azide

Pomalidomide 4'-PEG5-azide is the Pomalidomide (HY-123324)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide 4'-PEG5-azide can be connected to the ligand for protein by a linker to form PROTAC.

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Pomalidomide 4'-PEG5-azide Chemical Structure

Pomalidomide 4'-PEG5-azide Chemical Structure

CAS No. : 2624181-61-7

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Pomalidomide 4'-PEG5-azide Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Description

Pomalidomide 4'-PEG5-azide is the Pomalidomide (HY-123324)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide 4'-PEG5-azide can be connected to the ligand for protein by a linker to form PROTAC[1].

Molecular Weight

562.57

Formula

C25H34N6O9
CAS No.
SMILES

[N-]=[N+]=NCCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Pomalidomide 4'-PEG5-azide Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pomalidomide 4'-PEG5-azide2624181-61-7E3 Ligase Ligand-Linker ConjugatesCRBNlinkerPROTACcereblonPomalidomideInhibitorinhibitorinhibit

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HY-139333
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